Validation and Comparison of a Virtual Reality Protocol in Children Without Vestibular Pathology and Children With Chronic Vestibular déficits : Prospective Study ReViCHILD
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 140
- 试验地点
- 2
- 主要终点
- Degree of precision
研究概览
简要总结
Vestibular information is important in establishing a child's static and dynamic postural control. Any vestibular deficit can have major consequences on development, spatial cognition and quality of life.
In order to interact with the world around us, we must simultaneously integrate different sources of sensory informations (vision, hearing, perception of the body...). The brain integrates these different sensory components to form a unified and coherent perception: this is multisensory integration.
Multisensory integration has been studied using virtual reality in adults, in the "spatial orientation" team of the Center for Integrative Neurosciences and Cognition. These experiments were carried out on healthy subjects and in weightless situations (international space station or parabolic flight). However, no protocol has been developed in children or in subjects with vestibular deficit. Virtual reality is interesting for developing such a protocol because it creates multisensory stimulation capable of promoting visual and proprioceptive compensation of the vestibular deficit.
It induces an immersion of the patient in a virtual spatial and temporal environment difficult to carry out with traditional vestibular rehabilitation techniques. Its main advantage is that it is a fun and safe interactive diagnostic and therapeutic tool, which is particularly suitable for children. Being able to modulate certain sensory information using virtual reality, in children without vestibular function deficit and in children with vestibular function deficit, will make it possible to better understand the role of the vestibule in the construction of the self in relation to space and environment. In addition to the scientific aspect, the diagnostic and therapeutic benefits are potentially numerous.
The objective of the study is to determine a reliable, well-tolerated and age-appropriate virtual reality protocol in children without vestibular deficit and in children with chronic vestibular deficit, making it possible to study the hand-eye coordination.
详细描述
Vestibular information is important in establishing a child's static and dynamic postural control. Any vestibular deficit can have major consequences on development, spatial cognition and quality of life.
In order to interact with the world around us, we must simultaneously integrate different sources of sensory informations (vision, hearing, perception of the body ...). The brain integrates these different sensory components to form a unified and coherent perception: this is multisensory integration.
It is particularly important in children for the acquisition of sitting, standing and then walking. When a congenital vestibular deficit exists, adaptive behaviors using visual and proprioceptive inputs are set up.
Multisensory integration has been studied using virtual reality in adults, in the "spatial orientation" team of the Center for Integrative Neurosciences and Cognition. These experiments were carried out on healthy subjects and in weightless situations (international space station or parabolic flight). However, no protocol has been developed in children or in subjects with vestibular deficit. Virtual reality is interesting for developing such a protocol because it creates multisensory stimulation capable of promoting visual and proprioceptive compensation of the vestibular deficit.
It induces an immersion of the patient in a virtual spatial and temporal environment difficult to carry out with traditional vestibular rehabilitation techniques. Its main advantage is that it is a fun and safe interactive diagnostic and therapeutic tool, which is particularly suitable for children. Being able to modulate certain sensory information using virtual reality, in children without vestibular function deficit and in children with vestibular function deficit, will make it possible to better understand the role of the vestibule in the construction of the self in relation to space and environment. In addition to the scientific aspect, the diagnostic and therapeutic benefits are potentially numerous.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 7 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Minors aged 7 to 17 years (inclusive)
- •Volunteers adult
- •Information and consent of holders of parental authority of minors, minors and of adult subjects
- •Presence of unilateral or bilateral chronic vestibular pathology
- •Minor patients followed in consultation at Necker Hospital in the Pediatric ENT department
- •Adult patients followed at adult vestibulometry services (Lariboisière and Pitié Salpêtrière Hospitals)
- •No history of otological surgery and absence of vestibular pathology
- •Patients followed in consultation at Necker Hospital, siblings or adult parents
排除标准
- •Presence of an ophthalmological pathology (including refractive errors)
- •Presence of neurological pathology including epilepsy or any pathology that can alter mobility and interfere with the performance of tasks
研究组 & 干预措施
Children and adolescents patients with chronic vestibular deficits
Patients aged 7 to 17 years with chronic vestibular deficits
干预措施: Vestibular tests (Diagnostic Test)
Children and adolescents patients with chronic vestibular deficits
Patients aged 7 to 17 years with chronic vestibular deficits
干预措施: Virtual reality (Other)
children and adolescents controls
Patients aged 7 to 17 years without chronic vestibular deficits
干预措施: Vestibular tests (Diagnostic Test)
children and adolescents controls
Patients aged 7 to 17 years without chronic vestibular deficits
干预措施: Virtual reality (Other)
Adults without chronic vestibular deficits
干预措施: Vestibular tests (Diagnostic Test)
Adults without chronic vestibular deficits
干预措施: Virtual reality (Other)
Adults with chronic vestibular deficits
干预措施: Vestibular tests (Diagnostic Test)
Adults with chronic vestibular deficits
干预措施: Virtual reality (Other)
结局指标
主要结局
Degree of precision
时间窗: Day 0
Doing a task involving hand-eye coordination, in virtual reality, and in different sensory situations. Rate of errors during the test
Degree of reproducibility
时间窗: Day 0
Doing a task involving hand-eye coordination, in virtual reality, and in different sensory situations. Success rate for each task is measured
次要结局
- Compare the success rate in eye-hand coordination(Day 0)
- Correlate virtual reality results with vestibular test results(Day 0)
- Stratify responses to virtual reality by age(Day 0)
- Occurrence of side effects of virtual reality(Day 0)
- Children's satisfaction concerning the virtual reality protocol(Day 0)