Efficacy of Prokinetics With Split Dose of PEG in Morning Colonoscopic Bowel Preparation: A Randomized, Controlled Trial
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 152
- 试验地点
- 1
- 主要终点
- bowel cleaning quality according to Ottawa scale scores
研究概览
简要总结
In bowel preparation using split dose PEG, various adjuncts to colonic cleansing were proposed to improve colonic preparation cleansing. Prokinetics, as an adjunct, was included in a few studies. The investigators study was to show that sufficient dosage of prokinetics added to split dose of PEG improves the state of bowel preparation.
详细描述
This was a randomized, prospective, endoscopist-blinded clinical trial in which the efficacy of prokinetics coadministrated with split dose PEG on the bowel cleansing was inspected.
Endoscopists, who were blinded to the study group of the patient, immediately completed the Ottawa scale and the fluidity scale after procedure
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient who are scheduled for colonoscopy
排除标准
- •pregnancy,
- •breast feeding,
- •known or suspected bowel obstruction, and
- •known allergy to PEG or Itopride ,
- •presence of severe illness(renal failure, congestive heart failure, liver failure,), and
- •refusal of consent to participate in the study
研究组 & 干预措施
Split dose PEG with prokinetics
Bowel preparation using split-dose PEG with prokinetics
干预措施: itopride (Drug)
结局指标
主要结局
bowel cleaning quality according to Ottawa scale scores
时间窗: 3 months
次要结局
- procedure time and polyp detection rate(3 months)