CTRI/2023/08/057001尚未招募不适用
Outcome of New Onset Septic Shock in ICU population
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 41
- 试验地点
- 1
- 主要终点
- Mortality in ICU patients developing new onset septic shock
研究概览
简要总结
This is a prospective observational study in which we aim to study the incidence, ICU course and outcome in terms of 28 days mortality. The primary outcome measures will be 28 days mortality in ICU patients developing new onset septic shock. The secondary outcome will be need and duration for vasopressors, need and duration for renal replacement therapy, risk factors for 28 days mortality, source of infection, ICU and hospital length of stay.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 99.00 Year(s)（—）
- 性别
- All
入选标准
- •Patient admitted in Intensive care unit.
- •Developing septic shock after 48 hours of ICU admission.
- •Patients diagnosed with new onset septic shock according to sepsis 3 definition ( septic shock defined as suspected or confirmed infection plus hyperlactatemia ( more than 2 mmol per litre) and requirement of vasopressor to maintain a mean arterial pressure of 65 mmHg or higher after intravenous fluid resuscitation as per surviving sepsis guidelines.
排除标准
- •Patients below 18 years of age.
- •Patients developing shock within 48 hours of ICU admission.
- •Patients with End of life care.
结局指标
主要结局
Mortality in ICU patients developing new onset septic shock
时间窗: 28 days
次要结局
- Need & duration of vas opressors.(28 days)
- Need of renal replacement therapy & it’s duration(28 days)
- ICU & hospital length of stay.(28 days)
- Source of infection(28 days)
- Risk factors for 28 days mortality(28 days)
- Need of invasive mechanical ventilation & it’s duration(28 days)
- Effect of timing of appropriate antibiotics on mortality(28 days)
研究者
研究点 (1)
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