Multi Center Case Control Study on Multiple Risk Factors of Aplastic Anemia Based on EDC Data Management Platform
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,802
- 主要终点
- the items about daily Exposures
研究概览
简要总结
To ascertain the risk factors of AA in ZheJiang Province of China at the moment, especially the comprehensive multiple factors risks. The author conducted a case-control research included 338 AA cases and 1464 controls. Subjects were surveyed using same standard questionnaire including personal data, past histories of diseases, family history and histories of occupational and daily exposure to harmful substances. Single and multiple Logistic regression analyses were made using SPSS17.0 on the dates to study potential factors in the development of AA.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 1 Year 至 65 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All the patients of AA group met a AA diagnostic criteria；The control group were chosen from other departments who were under acute infection (such as pneumonia), acute abdominal emergency (such as appendicitis), cataract surgery;
- •1-65 years old, male or female;
- •Sign the informed consent.
排除标准
- •With myelodysplastic syndrome, leukaemia, multiple myeloma,megaloblastic anaemia, paroxysmal sleep hemoglobinuria disease blood disease, etc.
- •History of tumor, radiation or chemotherapy, once accept the immunological therapy, autoimmune diseases or allergic disease patients;
- •Patients with neurological diseases.
结局指标
主要结局
the items about daily Exposures
时间窗: January 2014
Whether living or working near chemical factory or ionizing radiation, whether living in newly decorated apartments/house, having pets/livestock
次要结局
- Individual Behaviours(January 2014)
- Occupational Exposures(January 2014)
- Individual Health Status(January 2014)
- Family disease history(January 2014)
研究者
Shengyun Lin
chief
Zhejiang Provincial Hospital of TCM