Risk Factors and Prognosis of Adverse Cardiovascular and Kidney Events After Coronary Intervention - Cardiorenal ImprovemeNt Registry II
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Cardio-Renal Syndrome
- Sponsor
- Guangdong Provincial People's Hospital
- Enrollment
- 184855
- Locations
- 1
- Primary Endpoint
- Contrast-Induced Acute Kidney Injury (CI-AKI 0.3)
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
As a multi-center, retrospective observation study in southern China, this study included the main study population of patients who underwent coronary angiography at 5 hospitals from Guangzhou, Shenzhen, Yangjiang, Maoming and Longyan from January 2000 to Decemeber 2020. The hospitalization information was collected in the form of direct derivation of the case, and cardiac and renal adverse events were collected through outpatient system. Data on all-cause death were obtained from the Guangdong Provincial Public Security and matched to the electronic Clinical Management System of the Guangdong Provincial People's Hospital records.
Detailed Description
This is a multi-center, retrospective observation study collecting data on 184855 coronary angiography patients from January 2000 to Decemeber 2020. Data regarding demographic information, admission diagnoses and history of present illness, biomarkers and details on preventive hydration and medications will be collected. The primary endpoint of this study is Adverse Cardiovascular and Kidney Events.
Investigators
Jiyan Chen
Director
Guangdong Provincial People's Hospital
Eligibility Criteria
Inclusion Criteria
- •Patients referred to CAG or PCI;
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Contrast-Induced Acute Kidney Injury (CI-AKI 0.3)
Time Frame: 48 hours
defined as a ≥ 0.3 mg/dL absolute increase in serum creatinine from baseline during the first 48 hours after the procedure
Secondary Outcomes
- The change of eGFR, calculate based on CrCl and serum cystatin C(48-72 hours)
- Cystatin C based CI-AKI (CI-AKI cyc)(24-48 hours)