Risk Factors and Prognosis of Adverse Cardiovascular and Kidney Events After Coronary Intervention - Cardiorenal ImprovemeNt Registry II
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 184,855
- 试验地点
- 1
- 主要终点
- Contrast-Induced Acute Kidney Injury (CI-AKI 0.3)
研究概览
简要总结
As a multi-center, retrospective observation study in southern China, this study included the main study population of patients who underwent coronary angiography at 5 hospitals from Guangzhou, Shenzhen, Yangjiang, Maoming and Longyan from January 2000 to Decemeber 2020. The hospitalization information was collected in the form of direct derivation of the case, and cardiac and renal adverse events were collected through outpatient system. Data on all-cause death were obtained from the Guangdong Provincial Public Security and matched to the electronic Clinical Management System of the Guangdong Provincial People's Hospital records.
详细描述
This is a multi-center, retrospective observation study collecting data on 184855 coronary angiography patients from January 2000 to Decemeber 2020. Data regarding demographic information, admission diagnoses and history of present illness, biomarkers and details on preventive hydration and medications will be collected. The primary endpoint of this study is Adverse Cardiovascular and Kidney Events.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients referred to CAG or PCI;
排除标准
- 未提供
结局指标
主要结局
Contrast-Induced Acute Kidney Injury (CI-AKI 0.3)
时间窗: 48 hours
defined as a ≥ 0.3 mg/dL absolute increase in serum creatinine from baseline during the first 48 hours after the procedure
次要结局
- The change of eGFR, calculate based on CrCl and serum cystatin C(48-72 hours)
- Cystatin C based CI-AKI (CI-AKI cyc)(24-48 hours)
研究者
Jiyan Chen
Director
Guangdong Provincial People's Hospital