跳至主要内容
临床试验/NCT03276650
NCT03276650已完成不适用

Admission of Adult-onset Still Disease Patients in the ICU: a French Retrospective Multicentric Study

Central Hospital, Nancy, France1 个研究点 分布在 1 个国家目标入组 45 人开始时间: 2017年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
45
试验地点
1
主要终点
number of patients

研究概览

简要总结

Since its first description in 1971, diagnosing adult-onset Still's disease (AOSD), a rare multisystemic disorder considered as a multigenic autoinflammatory syndrome, remains challenging. Rarely, AOSD may present severe systemic manifestations and require intensive care. The main purpose of the Stil ICU study is to make the first description of the epidemiology of critically ill AOSD patients. The investigators will use a retrospective cohort study design with dual recruitment strategies: (1) via the AOSD referral centres network and (2) via a French academic medical ICU network.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • AOSD (history of newly diagnosed)
  • ICU admission between January 2001 and June 2017

排除标准

  • adults under protection
  • admission in step-down unit

结局指标

主要结局

number of patients

时间窗: At inclusion

Number of patients fulfilling the inclusion criteria

次要结局

  • Mortality(through study completion, maximum 17,5 years after admission)
  • Number of rehospitalisation in ICU(through study completion, maximum 17,5 years after admission)
  • recurrent relapses(through study completion, maximum 17,5 years after admission)
  • APACHE II(24hour after ICU admission)
  • number of hospitalisation in internal medicine ward(through study completion, maximum 17,5 years after admission)

研究者

发起方
Central Hospital, Nancy, France
申办方类型
Other
责任方
Sponsor

研究点 (1)

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