Optic Disc Perfusion in Glaucoma Suspect and Primary Open Angle Glaucoma using Optical Coherence Tomography Angiography.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- To evaluate optic disc perfusion using Optical Coherence Tomography- Angiography in eyes with Primary Open Angle Glaucoma (POAG) and Glaucoma Suspects.
研究概览
简要总结
Glaucoma is considered as one of the leading causes of irreversible blindness in the world. Optic nerve head (ONH) perfusion may be associated with development of glaucoma. A reliable and reproducible clinical method for evaluating the optic nerve head perfusion will thus help us in early detection and monitoring of glaucoma. Optical Coherence Tomography Angiography is a new method of analysis based on high resolution, non-invasive imaging technique whereby retinal, choroidal and optic nerve head circulation can be visualised without the need to inject any contrast agent. The purpose of this study is to assess whether OCT Angiography is a reliable clinical method for evaluating the optic nerve head perfusion in Glaucoma suspect and Primary Open Angle Glaucoma(POAG) by comparing with healthy eyes and to correlate the functional vasculature parameters obtained from OCTA to the structural parameters obtained from Spectral–domain(SD) OCT RNFL thickness measurements.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 90.00 Year(s)（—）
- 性别
- All
入选标准
- •1 Age greater than 18 years.
- •2 Open iridocorneal angle on gonioscopy 3 Best corrected visual acuity of minimum 0.48 logMAR units or more.
排除标准
- •1 History of intra ocular surgery except glaucoma surgery and uncomplicated cataract surgery.
- •2 Secondary causes of glaucoma 3 Non glaucomatous optic neuropathies 4 Vascular or non-vascular retinopathies •Other ocular or systemic diseases that may affect vision.
结局指标
主要结局
To evaluate optic disc perfusion using Optical Coherence Tomography- Angiography in eyes with Primary Open Angle Glaucoma (POAG) and Glaucoma Suspects.
时间窗: on the day of enrollment into the study
次要结局
- 1.To evaluate association between vessel density measurements using OCT-Angiography and RNFL Analysis using SD-OCT in Primary Open Angle Glaucoma and Glaucoma suspect.2.To establish normative data for optic disc perfusion using OCT-Angiography.(1 year)