Effect of Copepod Oil Supplementation (Calanus Finmarchicus) on Endurance and VO2max in Healthy Obese Subjects
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 71
- 试验地点
- 2
- 主要终点
- maximal oxygen uptake (VO2max)
研究概览
简要总结
Copepod oil is extracted from the marine copepod Calanus finmarchicus, the dominant plankton species in the marine food web in the Norwegian Sea. Copepods constitute the largest renewable and harvestable resource in the Norwegian Sea and adjacent waters, and it is now developed knowledge and technology for sustainable harvesting of this "new" resource. The purpose of this study is to investigate whether Calanus copepod oil supplementation has an equivalent effect on maximal oxygen uptake in humans to that seen in experimental studies in mice.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •in good health
- •Body mass index (BMI) between 18,5 and 29,9
排除标准
- •Medical condition limiting VO2max (COPD or asthma).
- •diagnosed coronary artery disease
- •Any other significant medical condition
- •medication effecting exercise capacity (e.i. betablockers)
- •Pregnancy
- •Participation in other clinical trials
- •Shellfish allergies
- •Systolic blood pressure > 170 mmHG, or diastolic BP > 105 mmHG.
- •contraindications for maximal exercise testing
结局指标
主要结局
maximal oxygen uptake (VO2max)
时间窗: 6 months
Measured with indirect calorimetry at a treadmill (running/walking) with gradually increasing work load until exhaustion. After 10-15 min with warmup at 70% of maximal heart rate, work load will be increased every 1-2 minute and the changes maximal oxygen uptake (VO2) will be recorded automatically.
次要结局
- Self-reported physical activity(6 months)
- Body composition (InBody, Japan)(6 months)