DRKS00014715已完成不适用

Imaging Disease Progression in COPD - MR-COPD II

niversitätsklinikum Heidelberg Klinik Diagnostische und Interventionelle Radiologie0 个研究点目标入组 252 人开始时间: 2018年6月6日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Patients enrolled into the COSYCONET main cohort of COPD (Chronic Obstructive Pulmonary Disease) patients, having already participated in the COSYCONET subtrial with CT and MRI performed between December 2013 and July 2016 (MR-COPD I”, COSYCONET Subproject 7);
•MRI and CT images obtained in sufficient quality at baseline (MR-COPD-I”)

•Having undergone lung surgery (e.g. lung volume reduction, lung transplantation)
•Replaced pneumonia (antibiotic treatment necessary) in the last four weeks.
•Moderate or severe exacerbation requiring antibiotic treatment within the last 4 weeks prior to appointment
•Absence of informed consent
•Inability to understand the intention of the project
•Missing or incomplete MRI or CT examination in baseline (MR-COPD I).
•Insufficient quality of MRI and CT obtained at baseline (MR-COPD I)
•Contraindications to CT and MRI:
•Due to the strong magnetic field
•- patients with pacemaker
•- patients with incompatible metallic implants
•Due to the use of Gadolinium based contrast agent
•- acute and chronic renal insufficiency (GFR <40 ml / min according to MDRD calculation)
•Pregnancy
•Claustrophobia
•Acute psychoses or other conditions that make the perception of the patient appear limited

发起方

niversitätsklinikum Heidelberg Klinik Diagnostische und Interventionelle Radiologie