Prospective Non Randomized interventional study to compare the effect of spinal anaesthesia versus general anaesthesia on Blood Glucose concenteration in patients undergoing lower abdominal surgeries at SMS Medical College and Hospital,Jaipur
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 70
- 试验地点
- 2
- 主要终点
- Mean Blood Glucose Concenteration
研究概览
简要总结
The Etiology of hyperglycemia is multifactorial , but is thought primarily to be the result of activation of the sympathoadrenal system ,with contributions from the hypothalamus and adenohypophysis. The stress response triggers an increase in levels of plasma catecholamines and glucocorticoids ,which in turn lead to hyperglycemia . cortisol also has a huge impact on the glucose metabolism in stress, because by increasing glycogenolysis and glucogenesis it can lead to hyperglycemia . the aim of the study is t determine the significance of spinal anaesthesia in supressing the metabolic , and hemodynamic response to surgical stress during and after elective abdominal urological and orthopaedics surgery compared with the technique of general anaesthesia
研究设计
- 研究类型
- Interventional
- 分配方式
- Not Applicable
- 盲法
- Not Applicable
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)(—)
- 性别
- All
入选标准
- •1.Patients undergoing scheduled elective surgeries 2.patients willing to give informed written consent 3.ASA Grade 1 and 2.
排除标准
- •1.Any Cardiovascular disorder 2.Any Respiratory Disorder 3.diabetic patients 4.Hypertensive patients 5.Neurological disorders 6.Drug allergy , if any.
结局指标
主要结局
Mean Blood Glucose Concenteration
时间窗: 5 minutes before induction | 5 minutes after induction | 5 minutes before completion | 30 minutes after completion
次要结局
- Mean Hemodynamic variables(Baseline)
