Clinical Trial for the Effects of Joint Effusion on Proprioception
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Proprioceptive acuity in Knee Joint. Proprioceptive acuity (difference between the knee angles at the target and reproduced positions) was assessed by active repositioning of the lower limb after injection or no injection.
研究概览
简要总结
The purpose of this study is to assess the effects of joint effusion on proprioceptive status in patients with knee osteoarthritis (OA).
详细描述
Proprioception is a sensory modality that provides feedback on the internal status of the body and enables us to perceive joint position and motion.
Osteoarthritis (OA), also called degenerative joint disease, is a major musculoskeletal condition characterized by loss of articular cartilage that leads to pain and loss of function. The most commonly affected joint is the knee, and OA may result in changes that affect not only intracapsular tissues, but also periarticular tissues, such as ligaments, capsules, tendons, and muscles. Many studies have examined the proprioceptive status of knee OA, and subjects with knee OA are known to have impaired proprioception compared with age-matched controls.
Joint effusion is a common symptom associated with chronic degenerative joint condition, but the effects of effusion on knee joint proprioception have not been investigated in detail.
A volume of 20 mL of normal saline was injected into the knee joint cavity of subjects in the experimental group under ultrasonographic guidance. Proprioceptive acuity was assessed by active repositioning of the lower limb using an electrogoniometer to measure knee joint position sense (JPS) under both non-weight-bearing and weight-bearing conditions twice, with a 20-min rest interval.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Or at least two of criteria 2-6 established by the American College of Rheumatology (ACR):
- •Kellgren and Lawrence (K/L) grade ≥II
- •morning stiffness <30 min in duration
- •crepitus on movement of the knee joint
- •bony tenderness at the knee joint margins
- •palpable or visible bony enlargement
- •no palpable warmth.
排除标准
- •the presence of knee joint effusion determined by ultrasonography
- •a history of knee injury or surgery
- •a history of knee injection within 3 months
- •a history of inflammatory arthritis
- •taking anticoagulants
- •balance or gait disturbance
- •diabetes mellitus.
研究组 & 干预措施
Infusion
20cc saline infusion into the knee joint
干预措施: Normal saline (Procedure)
No infusion
干预措施: Normal saline (Procedure)
结局指标
主要结局
Proprioceptive acuity in Knee Joint. Proprioceptive acuity (difference between the knee angles at the target and reproduced positions) was assessed by active repositioning of the lower limb after injection or no injection.
时间窗: within one hour after intervention
次要结局
未报告次要终点