Can the Distribution of Low B-value and the NEX Influence the Pseudodiffusion Parameter Derived From IVIM in Brain?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 主要终点
- Parameters D* and f in healthy white matter or gray mater
研究概览
简要总结
Our research aims to reveal whether the low b-values distribution and the number of NEX for each b value will influence the accuracy of pseudodiffusion parameter derived from IVIM in brain.
详细描述
As an improved MRI technique, diffusion-weighted imaging (DWI) is considered the most sensitive for early pathological changes. Perfusion measurement has been shown to improve sensitivity and predictive value for tumor grading and prognosis, also as a predicator of recovery with reperfusion in patients of acute ischemic stroke.Our research aims to reveal whether the low b-values distribution and the number of NEX for each b value will influence the accuracy of pseudodiffusion parameter derived from IVIM in brain.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 25 Years 至 35 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •no hypertension or cerebral vascular diseases,
- •no systemic metabolic disease;
- •no infection or fever;
- •no use of corticosteroid drugs;
- •no MRI contraindication.
排除标准
- 未提供
结局指标
主要结局
Parameters D* and f in healthy white matter or gray mater
时间窗: 2-3 days
次要结局
未报告次要终点