Assessment ofDermatological Abnrmalities in Beta-thalassemia Major in Assiut University Pediatric Hospital
试验速览
- 阶段
- 不适用
- 入组人数
- 125
- 主要终点
- The percentage of patients with dermatological disorders due to iron overload Iron overload cause dermatological abnormalities
研究概览
简要总结
to study the frequency and pattern of dermatological abnormalities in egyptian childern with beta thalassemia.relationof abnormalities to duration of disease and frequency of transfusion
详细描述
thalassemia refers to agroup of inherited disease characterized by decreased or absent synthesis of normal globin .skinvdisorders are usually neglected and frequently underdiagnosed among these patients.skin disease specially pruritus and xerosis are observed highly frequently in patients with beta-thalassemia.pityriasis alba is arelatively common skin disorder.the trophic skin changes and leg ulcers occurred after the age of 15 years
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 2 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- •patient with other hemolytic anemia. childern with any abnormalities prior to the diagnosis of thalassemi
结局指标
主要结局
The percentage of patients with dermatological disorders due to iron overload Iron overload cause dermatological abnormalities
时间窗: one month
the number of patients who develop any dermatological disorder as a result of iron overload after frequent blood transfusion
次要结局
未报告次要终点
研究者
Neveen Mamdoh Farag
Principal investigator
Assiut University