The Comparison of the Analgesic Efficacy and Hemodynamic Effects of Paravertebral Block Compared With Paravertebral and Intercostal Nerve Block for Thoracotomy in Adults: A Randomized Controlled Trail
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Blood Pressure
研究概览
简要总结
Thoracotomy is a surgical procedure associated with severe post operative pain during the first day of surgery and is responsible for prolonged hospital stay, patient dissatisfaction and delayed return to normal activities along with increased morbidity and mortality. Investigators intend to compare the efficacy of two analgesic interventions (continuous infusion of paravertebral block (PVB) after loading dose compared with intercostal nerve block and continuous infusion of PVB without loading dose) on postoperative thoracotomy pain. The results of this study will direct the investigators to find the best practice methods which will reduce the postoperative thoracotomy pain, the overall cost of pain management and length of patient's hospital stay.
详细描述
Objective To compare the safety, efficacy for pain relief and hemodynamic changes of two analgesic interventions(continuous infusion of Paravertebral block (PVB) after loading dose compared with intercostal nerve block and continuous infusion of PVB without loading dose)
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •All ASA I-IV adult patients between the ages of 18-70 years scheduled for elective thoracotomy
- •Either sex
排除标准
- •Neurological or psychiatric diseases
- •Emergency Procedures.
- •Language barrier
- •Patients under chronic treatment with opioids
- •Patients with hypersensitivity to bupivacaine
- •Coagulation disorders.
- •Unwilling to participate.
- •Patient previously involved in other studies
结局指标
主要结局
Blood Pressure
时间窗: 24 hours
Blood pressure in mmHg
Pain Score
时间窗: 24 hours
Visual Analogue Scale (VAS) pain Score in cm (0cm = No pain and 10 cm= Worst pain possible)
Heart Rate
时间窗: 24 Hours
Heart rate per minute
次要结局
- Sedation score(24 hours)
- Total postoperative narcotic consumption(24 hours)
研究者
Kumar Sundeep
Trainee Medical Officer Anaesthesiology
Aga Khan University Hospital, Pakistan
