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临床试验/NCT01972802
NCT01972802Unknown不适用

International Cancer of the Head and Neck, Genetics and Environment (InterCHANGE) Study

National Taiwan University Hospital1 个研究点 分布在 1 个国家目标入组 900 人开始时间: 2011年1月最近更新:
适应症

试验速览

阶段
不适用
入组人数
900
试验地点
1
主要终点
head and neck cancer risk factor

研究概览

简要总结

Our overall objective is to understand the role of lifestyle factors, genetics and HPV infection in the development and prognosis of head and neck cancer particularly in Asia.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age 18~80 Incident head and neck cancer patients
  • Oral, oropharynx and hypopharynx (C00-C14)
  • Laryngreal cancer (C32)
  • *Esophageal cancer if possible (C15)

排除标准

  • Salivary gland (C07-C08)
  • Nasopharynx (C11)
  • Thyroid (C79.3)

结局指标

主要结局

head and neck cancer risk factor

时间窗: Four years

evaluate the association between certain environmental exposures (e.g. cigarette smoking, alcohol drinking, betel nut chewing...) and head and neck cancers,assess the effect of genetic factors, including both SNP and copy number variation (CNV) through analysis of both main effect and gene-gene interaction

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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