NCT06867900进行中（未招募）不适用
Unexplained Recurrent Pregnancy Loss: New Therapeutic Perspectives
Fondazione Policlinico Universitario Agostino Gemelli IRCCS2 个研究点 分布在 1 个国家目标入组 22 人开始时间: 2021年1月1日最近更新:
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 22
- 试验地点
- 2
- 主要终点
- Assessment of Endometrial inflammation in RPL women
研究概览
简要总结
Evaluation of gut permeability and endometrial inflammasome NLRP3 in women with unexplaid recurrent pregnancy loss before-after administration of Bifidobacteriumlongum ES1.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Idiopathic recurrent pregnancy loss
- •Genetic predisposition to celiac disease
排除标准
- 未提供
研究组 & 干预措施
Bifidobacterium Longum
Experimental
干预措施: Bifidobacterium Longum ES1 (Dietary Supplement)
结局指标
主要结局
Assessment of Endometrial inflammation in RPL women
时间窗: 3 months
Analysis of the inflammasome NALP3 expression and activation in serum and endometrial fluid in women with unexplained recurrent pregnancy loss compared to women with uncomplicated pregnancy history.
Assessment of Gut permeability status in RPL women
时间窗: 3 months
Analysis of zonulin expression and activation in serum and endometrial fluid in women with unexplained recurrent pregnancy loss compared to women with uncomplicated pregnancy history.
次要结局
未报告次要终点
研究者
研究点 (2)
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