NCT04455256
Completed
Not Applicable
Endoplasmic Reticulum Stress in Recurrent Pregnancy Loss
Kanuni Sultan Suleyman Training and Research Hospital1 site in 1 country90 target enrollmentMarch 20, 2020
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Recurrent Pregnancy Loss
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
- Enrollment
- 90
- Locations
- 1
- Primary Endpoint
- Show the effect of endoplasmic reticulum stress on recurrent pregnancy loss
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
To evaluate endoplasmic reticulum stress in women with recurrent pregnancy loss and those who had healthy births in the same age group. The level of the unfolded protein X box binding protein 1 (XBP-1) is measured. It is aimed to show the effect of endoplasmic reticulum stress on recurrent pregnancy loss.
Investigators
Pınar Yalcin bahat
Principal Investigator
Kanuni Sultan Suleyman Training and Research Hospital
Eligibility Criteria
Inclusion Criteria
- •with three or more miscarriages before 20 th week of gestation
- •had no chronic or acute inflammatory disease
- •used no steroids, anti-inflammatory, or antioxidant medications
Exclusion Criteria
- •had inflammatory diseases
- •had systemic disease
- •Anatomical abnormalities, infectious, endocrine, or genetic etiologies
Outcomes
Primary Outcomes
Show the effect of endoplasmic reticulum stress on recurrent pregnancy loss
Time Frame: 3 months
Serum value (pg / mL) of x box binding protein (XBP-1), which is one of the unfolded proteins indicating endoplasmic reticulum stress, is measured.
Study Sites (1)
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