NCT04455256已完成不适用
Endoplasmic Reticulum Stress in Recurrent Pregnancy Loss
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Show the effect of endoplasmic reticulum stress on recurrent pregnancy loss
研究概览
简要总结
To evaluate endoplasmic reticulum stress in women with recurrent pregnancy loss and those who had healthy births in the same age group. The level of the unfolded protein X box binding protein 1 (XBP-1) is measured. It is aimed to show the effect of endoplasmic reticulum stress on recurrent pregnancy loss.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •with three or more miscarriages before 20 th week of gestation
- •had no chronic or acute inflammatory disease
- •used no steroids, anti-inflammatory, or antioxidant medications
排除标准
- •had inflammatory diseases
- •had systemic disease
- •Anatomical abnormalities, infectious, endocrine, or genetic etiologies
结局指标
主要结局
Show the effect of endoplasmic reticulum stress on recurrent pregnancy loss
时间窗: 3 months
Serum value (pg / mL) of x box binding protein (XBP-1), which is one of the unfolded proteins indicating endoplasmic reticulum stress, is measured.
次要结局
未报告次要终点
研究者
Pınar Yalcin bahat
Principal Investigator
Kanuni Sultan Suleyman Training and Research Hospital
研究点 (1)
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