CTRI/2023/08/056500尚未招募2/3 期
Comparative evaluation of Psidium guajava leaf powder with Injectable Platelet Rich Fibrin & Demineralized Freeze-dried Bone Allograft with Injectable Platelet Rich Fibrin in the treatment of periodontal intrabony osseous defects: A Clinico-Radigraphic Study
未提供1 个研究点 分布在 1 个国家目标入组 28 人开始时间: 2023年8月31日最近更新:
适应症
试验速览
- 阶段
- 2/3 期
- 状态
- 尚未招募
- 入组人数
- 28
- 试验地点
- 1
- 主要终点
- Probing pocket depth(PPD), Clinical Attachment Level
研究概览
简要总结
The current study evaluated and compared the efficacy of Psidium guajava leaf powder plus iPRF versus DFDBA plus iPRF in the treatment of periodontal intrabony osseous defects by CBCT.
The following clinical parameters will be evaluated:
-
Plaque index (Silness and Loe)
-
Gingival index (Loe and Silness)
-
Probing pocket depth (PPD)
-
Clinical attachment loss (CAL)
Assessment will be done at baseline, 3 and 6 months.
For a sample size of 28 sites, 14 sites per group.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with stage III periodontitis assessed by probing pocket depth (PPD) ≥ 6mm, interdental clinical attachment loss (CAL) ≥ 5mm.
- •Patients with two or three wall intraosseous defects in either maxillary or mandibular arch or interarch.
排除标准
- •Patients with history of systemic diseases, allergies or drug usage.
- •Patients who have undergone periodontal treatment in previous 6 months.
- •Pregnant or lactating women.
- •Smokers, tobacco chewers and patients with poor oral hygiene index (PI>1.5) will be excluded from the study.
- •In addition, tooth with caries, mobility > grade II will be excluded.
结局指标
主要结局
Probing pocket depth(PPD), Clinical Attachment Level
时间窗: baseline 3 & 6 months
(CAL)
时间窗: baseline 3 & 6 months
次要结局
- Plaque Index (PI), Gingival Index (GI)(baseline 3 & 6 months)
研究者
研究点 (1)
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