NL-OMON31352已完成不适用
ocal microvascular reactivity to Acetylcholine in patients with essential hypertension: possible interactions with the local renin-angiotensin system. - Local microvascular reactivity to Ach in hypertensive patients
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 32
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Inclusion criteria hypertensive patients:
- •- Age:18-65 year
- •- Caucasian
- •- Untreated blood pressure > 140/90 mmHg
- •- In consultation with the internist, anti-hypertensive medication will be
- •stopped 3 weeks prior to the start of the experiment. ;Inclusion criteria normotensive volunteers:
- •- Age:18-65 year
- •- Caucasian
- •- Blood pressure <140/90 mmHg
排除标准
- •- Secondary hypertension
- •- Diabetes mellitus according to the criteria of the ADA
- •- Kidney failure: serum creatinine > 150 µmol/l
- •- Unable to stop blood pressure lowering medication during a period of
- •- Use of blood cholesterol lowering medication
- •- (Hypertensive) retinopathy, glaucoma or conjunctival disease
- •- Connective tissue disease
- •- Contact lenses
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