Effect of a single dose of Pregabalin on intraoperative hemodynamic changes and duration of analgesia in spinal anesthesia for tibial bone fracture orthopedic surgery

Deputy for research Zahedan University of Medical Sciences0 个研究点目标入组 120 人开始时间: 待定最近更新: 2018年2月22日

适应症

试验速览

暂无简介。

•The non-emergency patients ASA class 1; Age 20 to 70 years; candidates for orthopedic surgery tibia fracture; the prior written consent from patient; social class and level of consciousness that patient is able to cooperate ;
•Exclusion criteria were the beginning of the study:
•hemodynamic status is affected with diseases or conditions such as heart disease, diabetes, renal ;The history of allergy to gabapentin or Pregabalin, drug use, regular use of alcohol or smoking more than 5 years, the diseases of the brain and nerves ; spinal anesthesia during surgery after more than ninety minutes ; patients who require drugs that affect hemodynamic ; pregnancy ; refusal of doing research and refusal of spinal anesthesia patients ; patients with coagulopathy ; infection in site of the spinal anesthesia ; any interference with the absorption of oral drugs that can cause digestive disorders ; The disease affects the feeling of pain, such as diabetes, drug addiction ; Monitor the patient is indicative of Abnormal pulse , mean arteria presure ; The need for analgesics for pain relief
•Exclusion criteria during the study:
•Abnormal bleeding during surgery ; Intraoperative cardiovascular and brain complications ; Monitor the patient is indicative of abnormal pulse, mean arterial pressure.

发起方

Deputy for research Zahedan University of Medical Sciences