NCT00971555已完成不适用
Thyroid Function in Late Preterm Infants in Relation to Severity of Illness
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- Correlation of total T4 and TSH with gestational age, birth weight, and mode of delivery.
研究概览
简要总结
Transient hypothyroxinemia (TH) is a condition characterized by low levels of serum thyroxine (T4) and normal levels of thyroid stimulating hormone (TSH). TH in premature infants has been found to be related to severity of illness. T4 levels in very low birth weight infants born prematurely has been found to be inversely correlated to severity of illness. In very low birth weight infants, TH has been associated with poor outcomes. Little is known about thyroid function in late preterm infants.
Hypotheses:
- Ill late preterm infants will have lower total T4 levels than healthy late preterm infants.
- Total T4 and possibly TSH levels will be inversely correlated with short-term outcomes.
- Late Preterm infants born by cesarean section will have lower T4 levels compared to those born by vaginal birth.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 7 Days（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •any infant born between 34 0/7 weeks and 36 6/7 weeks gestation born at Christiana Hospital
排除标准
- •outborn infants
- •infants with major congenital anomalies
结局指标
主要结局
Correlation of total T4 and TSH with gestational age, birth weight, and mode of delivery.
时间窗: First week of life
次要结局
未报告次要终点
研究者
研究点 (1)
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