Implementing Vancomycin Reducing Practices (VRP) in Preterm Infants
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 13
- 试验地点
- 26
- 主要终点
- Fidelity of VRP use
研究概览
简要总结
This multi-center, cluster randomized study aimed at improving implementation of vancomycin reducing practices (VRP) in neonatal intensive care units (NICUs). Sites will be recruited and randomized to receive either external facilitation or no external facilitation to assess the effect on center-level fidelity to the core components of VRP implementation. Interventions available to both study arms are directed at hospital staff and includes identification of local champions, educational outreach, unit-level audit & feedback, and use of a clinical decision support tool.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Level III NICU
- •Affiliated with Kaiser Permanente Northern California (KPNC) or Children's Hospital of Philadelphia Newborn Care Network (CNBCN)
- •Recruited by study team
排除标准
- •Site not recruited for the study
结局指标
主要结局
Fidelity of VRP use
时间窗: 2.5 years - From beginning of implementation phase to the end of the sustainment phase
Proportion of late onset sepsis (LOS) evaluations performed with high fidelity. High fidelity is defined when the evaluation follows all three core components of VRP use.
次要结局
- Appropriateness/acceptability(2.5 years - From beginning of implementation phase to the end of the sustainment phase)
研究者
Sagori Mukhopadhyay
Principal Investigator, Attending Neonatologist, Associate Professor of Pediatrics
Children's Hospital of Philadelphia