Effects of Flexi Band Resistance Training Versus Different Electromyostimulation Exercise Programs in Patients With the Diagnosis of Malignant Diseases
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 试验地点
- 2
- 主要终点
- Muscle strength
研究概览
简要总结
The purpose of this study is to investigate the effects of a 12-week flexi band resistance training program compared to different whole-body electromyostimulation (WB-EMS) exercise programs on muscle strength, body composition (in particular muscle mass), cardiorespiratory fitness, inflammation, and patient-reported subjective outcomes (e.g. quality of life, fatigue, performance status) in patients with malignant disease undergoing curative or palliative anti-cancer treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •malignant disease (solid or hematological cancer): head and neck cancer, colorectal carcinoma, small intestinal cancer, gastric cancer, oesophageal cancer, pancreas carcinoma, liver cell carcinoma, cholangiocarcinoma, lung cancer, breast cancer, cervix cancer, ovarian cancer, prostate cancer, renal cell carcinoma, malignant melanoma, patients with leukaemia and malignant lymphomas or Graft-versus-Host-Disease after bone marrow transplantation
- •ongoing or planned curative or palliative anti-cancer therapy
- •ECOG-Status 0-2
排除标准
- •simultaneous participation in other nutritional or exercise intervention Trials
- •bone metastases with high fracture risk
- •cardiovascular disease
- •use of anabolic medications
- •severe neurological or rheumatic diseases
- •skin lesions in the area of electrodes
- •energy active metals in body
- •pregnancy
- •acute vein thrombosis
结局指标
主要结局
Muscle strength
时间窗: 12 weeks
Muscle strength of the five major muscle groups (chest, upper back, lower back, abdominals, legs) will be assessed by using specific strength-training devices and estimated using the one Repetition Maximum (1-RM, the maximum amount of weight \[kg\] that can be lifted for one repetition)
次要结局
- Muscle Mass(12 weeks)
- Fat Mass(12 weeks)
- Total Body Water(12 weeks)
- Cardiorespiratory Fitness (CRF)(12 weeks)
- Inflammation status(12 weeks)
- Patient-reported performance status-1(12 weeks)
- Patient-reported performance status-2(12 weeks)
- Patient-reported Quality of Life (QoL)(12 weeks)
- Patient-reported Fatigue(12 weeks)
- Patient-reported Physical Activity(12 weeks)
- Objective Physical Activity(12 weeks)
- Cardiometabolic Risk Profile (Metabolic Syndrome Z-Score, MetS)(12 weeks)