Title in Norwegian: Sunn og Frisk. En Studie av Helseeffekter av Fiskeinntak i Overvektige Voksne (FINS)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 183
- 试验地点
- 1
- 主要终点
- Changes in metabolic status (glucose, lipids, inflammation)
研究概览
简要总结
It has previously been observed that increased fish intake improves the metabolic health of overweight and obese adults, and animal protein improved metabolic health of obese rats. In this project the investigators will investigate whether increased intake of fish or meat improves metabolic health in overweight/obese adults aged 20-55 years when replacing processed food. The hypothesis is that increased intake of unprocessed fish or meat will improve metabolic health in adults as measured by glucose tolerance, lipid metabolism and inflammatory markers.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •BMI > 27
- •20-55 years
排除标准
- •diagnosed diseases such as diabetes, CVD, intestinal diseases, arthritis
- •prescription medications affecting the metabolism of glucose, lipids or the immune system
- •use of supplements containing long chain n-3 fatty acids
- •high intake of fish
- •food allergy
结局指标
主要结局
Changes in metabolic status (glucose, lipids, inflammation)
时间窗: Baseline and end of intervention (12 weeks)
The effects of fish intake on glucose homeostasis, lipid metabolism and inflammation will be assessed.
次要结局
- Changes in plasma concentrations of amino acids and their metabolites(Baseline and end of intervention (12 weeks))
- Changes in plasma concentrations of vitamins(Baseline and end of intervention (12 weeks))
研究者
Oddrun Anita Gudbrandsen
Researcher
University of Bergen