NL-OMON25659尚未招募不适用
Rediscovery of metformin for thechronic disabling auto-inflammatory disease Hidradenitis Suppurativa
适应症
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- ZonMw
- 入组人数
- 62
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Age =18 years at baseline
- •A diagnosis of HS for at least 1 year prior to baseline
- •mild to moderately active disease defined by a HS Physician Global Assessment (HS-PGA) score of 2-3 and the Refined Hurley classification of mild to moderate at baseline
- •Indication for systemic therapy; i.e. uncontrolled disease under conventional topical therapy.
- •Able and willing to give written informed consent and to comply with the study requirements
排除标准
- •Pregnant and lactating women
- •Concomitant diabetes mellitus
- •Use of antibiotics within 14 days prior to baseline
- •Use of immunosuppressing/modulating therapies within 28 days prior to baseline
- •A known allergy to metformin or doxycycline or any of the ingredients metformin or doxycycline
研究者
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