Asthma Exacerbation and Helium-3 MRI
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 发起方
- 试验地点
- 1
- 主要终点
- Image and quantify variation in asthmatic lungs at 0, 6 months, and 12 months
研究概览
简要总结
The goal of this research is to use Helium-3 MRI to see the changes in airflow of the lungs at different times of an attack. These three stages are immediately after the attack, 1 month later and 4-6 months later.
详细描述
Asthma is a pulmonary disorder that affects millions of people each year. The exact method of exacerbation is still under some discussion. Currently there is no cure for the disorder but treatment is of a wide variety.
This study is meant to image the asthmatic lung at various time points post exacerbation. Since pulmonary imaging is currently limited to radiation techniques, this method will allow exacerbated images without the unnecessary exposure to radiation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Asthmatics
All subjects will be asthmatics that have had an exacerbation (asthma attack) no more than 48 hours before the imaging session.
干预措施: Helium-3 (Drug)
结局指标
主要结局
Image and quantify variation in asthmatic lungs at 0, 6 months, and 12 months
时间窗: 1 year
次要结局
未报告次要终点
研究者
Mitchell Albert
Director of Advanced MRI Center, UMASS Medical Sch
University of Massachusetts, Worcester