Observational Study to Determine the Association Between Self-rated, Perceived Immune Fitness (Using Questionnaire) With Biological Assessment of Immune Fitness (Immune Signatures in the Blood).
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Relative quantification of immune protein in plasma
研究概览
简要总结
The overall objective of the study is to determine whether self-rated, perceived immune fitness (using questionnaire) is associated with biological assessment of immune fitness (immune signatures in the blood).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 35 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Ability to understand and sign the informed consent
- •Healthy adult men and/or women, 35-65 years old
- •BMI >18 and <30 kg/m2
排除标准
- •Volunteer who cannot be expected to comply with the protocol
- •Individuals with self-reported chronic disease; or who have any clinical condition which the investigator deems relevant for exclusion from the study,
- •Individuals with an impaired immune system that may confound immune response testing; i.e. any condition that impairs participant immune response through either the condition itself or through the treatment of the condition,
- •Family or hierarchical relationships with Clinical Innovation Lab at Nestlé Research, Lausanne, Switzerland
结局指标
主要结局
Relative quantification of immune protein in plasma
时间窗: 6 - 12 months after the start of the trial
Proteomic analysis in plasma by proximity extension assay
Amount of cytokines expressed by peripheral blood mononuclear cells
时间窗: 6 - 12 months after the start of the trial
Cytokine quantification by proximity extension assay
Amount of analytes in serum
时间窗: 6 - 12 months after the start of the trial
Blood chemistry
Percentage of different immune cell types in whole blood
时间窗: 6 - 12 months after the start of the trial
Immune cell type profiling in whole blood by mass cytometry
次要结局
未报告次要终点