跳至主要内容
临床试验/NCT05738668
NCT05738668进行中(未招募)不适用

Clinical-immunological Features of Anti-NMDAR Encephalitis

Hospices Civils de Lyon1 个研究点 分布在 1 个国家目标入组 400 人开始时间: 2022年2月1日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
400
试验地点
1
主要终点
Modified Rankin scale (mRS)

研究概览

简要总结

Using a retrospective cohort of 501 patients with anti-NMDAR encephalitis to assess clinical and immunological prognostic biomarkers

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

接受健康志愿者

入选标准

  • Patient with neurological disorder
  • Patient with NMDAR antibodies in sera or CSF

排除标准

  • - No available clinical data
  • Patient without NMDAR antibodies or neurological disorder

结局指标

主要结局

Modified Rankin scale (mRS)

时间窗: Baseline

Scale for measuring the degree of dependence in the daily activities of people who have suffered of neurological disability. 0 - No symptoms. 1. - No significant disability. Able to carry out all usual activities, despite some symptoms. 2. - Slight disability. Able to look after own affairs without assistance, but unable to carry out all previous activities. 3. - Moderate disability. Requires some help, but able to walk unassisted. 4. - Moderately severe disability. Unable to attend to own bodily needs without assistance, and unable to walk unassisted. 5. - Severe disability. Requires constant nursing care and attention, bedridden, incontinent. 6. - Dead.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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