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临床试验/NCT02980939
NCT02980939已完成不适用

The Role of Hydration on Exercise Performance - ODIN

University of Arkansas, Fayetteville2 个研究点 分布在 1 个国家目标入组 11 人开始时间: 2016年11月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
11
试验地点
2
主要终点
5km - Cycling Time Trial

研究概览

简要总结

During exercise in the heat, there is a need to replenish fluids in order to avoid dehydration and decrease the risk for heat illness. What drives this urge to drink is the thirst mechanism. Following ingestion of fluids, there is an inhibition of thirst before there is a replenishing of fluids. However, there is little scientific evidence of where thirst is inhibited, if this thirst inhibition is augmented by exercise and how thirst itself influence exercise performance. Further, during rehydration studies, it is very difficult to successfully blind a subject to their drinking/hydration protocol. Previous studies that have blinded a subject to their drinking have used various methods such as intravenous fluid administration and/or nasogastric tubes. Therefore, the purpose of this research is to examine the mechanistic roles thirst inhibition plays while exercising in the heat while undergoing intravenous fluid administration. Specific attention will be directed to the cardiovascular and thermoregulatory function of the individuals. All blood, cardiovascular, thermoregulatory, and perceptual measures are shown in the diagram below.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Prevention
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 45 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • Cycling Racing History category 3 or higher USA cycling certification
  • maximal oxygen uptake >55 ml/kg/min

排除标准

  • History of heat stroke
  • Renal, cardiovascular, metabolic diseases
  • Regular medication

结局指标

主要结局

5km - Cycling Time Trial

时间窗: 2hour

Time to completion 5 km cycling time trial in the heat

次要结局

  • Rectal Temperature(2hour)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Stavros Kavouras

Associate Professor

University of Arkansas, Fayetteville

研究点 (2)

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