Impact of Hospitalization on High-sensitivity Cardiac Troponin T Concentrations Depending on Disease Severity (Inpatient Troponin T)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 177
- 试验地点
- 1
- 主要终点
- Difference of the hs-cTnT concentration at hospitalization and after discharge
研究概览
简要总结
We aim to examine, whether hospitalization is associated with higher high-sensitivity cardiac troponin T (hs-cTnT) serum concentrations in patients without a cardiac disease.
详细描述
High-sensitivity cardiac troponin T (hs-cTnT) values will be obtained in hospitalized patients a) without a diagnosed or suspected cardiac disease, and b) with an acute medical condition that is not commonly associated with an increase of hs-cTnT concentrations. As a reference, a second sampling of blood for an analysis of the hs-cTnT serum concentration will be obtained in the same patients after discharge (60 days after hospitalization).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •hospitalization due to a non-cardiac disease
- •age ≥ 50 years
排除标准
- •diagnosed or suspected cardiac disease
- •acute medical conditions commonly associated with a myocardial injury (e.g. circulatory shock, sepsis, pulmonary embolism, cerebral infarction, acute renal failure)
结局指标
主要结局
Difference of the hs-cTnT concentration at hospitalization and after discharge
时间窗: 60 days
次要结局
- Difference of the hs-cTnT concentration at hospitalization and after discharge in acute medical conditions of low severity(60 days)
- Difference of the hs-cTnT concentration at hospitalization and after discharge in acute medical conditions of medium severity(60 days)
- Difference of the hs-cTnT concentration at hospitalization and after discharge in acute medical conditions of high severity(60 days)
- Prediction of 1-year-mortality by hs-cTnT concentration(1 year)
- Prediction of 1-year-hospitalization rate due to a cardiovascular disease by hs-cTnT concentration(1 year)
研究者
Rolf Wachter
Professor MD
University of Leipzig