Oxygen Partial Pressure and Lung Function After Orthopedic Surgery
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Oxygen partial pressure
研究概览
简要总结
Hypoxia and reduced oxygen partial pressure is commonly occurring after abdominal surgery. This study aims to investigate whether similar changes also occur after orthopedic surgery in the form of upper limb surgery.
Inclusion: 60 patients undergoing orthopedic surgery in the form o knee-, hip-, shoulder- or elbow surgery.
Exclusion: Dementia or cognitive impairment that makes it impossible to participate in studies.
Arterial blood gas and lung function are undertaken before surgery, the day after surgery and at follow-up.
详细描述
Postoperative hypoxia complicates 30% - 50% of abdominal surgeries. People at particular risk for postoperative pulmonary complications including severe hypoxia are those who undergo abdominal surgery, emergency surgery or have a respiratory failure due to chronic lung disease including obstructive sleep apnea. The cause of postoperative restrictive lung function and hypoxia is unknown. Previous studies report that PaO2 decreases by an average of 2 kPa after abdominal surgery, while PaCO2 is unchanged and vital capacity decreases by 35%. The effect of orthopedic surgery on oxygen and carbon dioxide partial pressure and lung function has previously not been investigated. This study aims to investigate possible changes in oxygen partial pressure and vital capacity after orthopedic surgery.
Design: Prospective cohort study
Inclusion: 60 patients undergoing orthopedic surgery in the form o knee-, hip-, shoulder- or elbow surgery..
Exclusion: Dementia or cognitive impairment that makes it impossible to participate in studies.
Method: Blood gas measurements and Lung function (Vital capacity and FEV1) The day before surgery, the day after surgery and at follow-up.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients undergoing shoulder or elbow surgery -
排除标准
- •Dementia or cognitive impairment that makes it impossible to participate in studies. Not willing to participate
结局指标
主要结局
Oxygen partial pressure
时间窗: 1 day
Change in oxygen partial pressure after surgery
次要结局
- Vital capacity(1 month)
- Oxygen partial pressure(1 month)
- Carbon dioxide partial pressure(1 month)
- Forced expiratory volume in one second(1 month)
研究者
Karl A Franklin
Profesor, Consultant surgeon
Umeå University