Assessing the Feasibility of Screening and Treating Anxiety and Depression in the Bone Marrow Transplant Population
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Systematic screening for depression and anxiety using the Hospital Anxiety and Depression Scale
研究概览
简要总结
The primary purpose of this study is twofold: (1) to assess the feasibility of screening adult hematopoietic stem cell transplantation (HSCT) candidates for psychiatric comorbidity (depression and anxiety), and (2) to assess the feasibility of treating depression and anxiety in adult HSCT candidates through a collaborative care algorithm. The ultimate goal of this project is improving HSCT outcomes for allogeneic HSCT candidates by improving identification and treatment of depression and anxiety disorders.
详细描述
Enrollment and depression and anxiety symptom screening:
All patients who are candidates for allogeneic transplantation and have a scheduled "Pre-Admission Visit" at UNC will be screened by study team to assess if they are eligible for participation. At their "Pre-Admission Visit" patients will be approached for enrollment in the study. Patients who provide written informed consent will complete the Hospital Anxiety and Depression Scale (HADS) survey at that time. If patients screen positive on the HADS (meaning a score of 8 or greater in the anxiety or the depression sections), they will be offered treatment within a collaborative care model intervention. If patients score less than 8 on the HADS survey (negative for symptoms of anxiety or depression) at the Pre-Admission Visit, they will not be offered treatment on study. Their medical records will still be abstracted periodically to follow post-transplant outcomes.
The Collaborative Care Model:
The collaborative care model is a team-delivered treatment program and will be provided by a treatment team of HSCT advanced practice providers (APP), HSCT physician, Comprehensive Cancer Support Program (CCSP) clinicians, and a psychiatrist. The collaborative care treatment intervention will be offered if patients score positive (score of 8 or greater) on the HADS. The collaborative care intervention includes medication consideration, therapy evaluation, and referral to psychiatry if needed.
Treatment Options in the Collaborative Care Model:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •hematological or non-hematological malignancy
- •plan to receive an allogeneic stem cell transplant
- •patient at UNC's ambulatory BMT clinic
- •able to complete self-report measures
- •English speaking
排除标准
- •plan to receive an autologous transplant
- •plan to receive allogeneic transplant for a non-malignancy
- •unable to complete self report measures in English
- •pre-existing diagnoses of bipolar affective disorder, schizoaffective disorder or schizophrenia
结局指标
主要结局
Systematic screening for depression and anxiety using the Hospital Anxiety and Depression Scale
时间窗: Day 0
Assess the feasibility of systematic screening for depression and anxiety using the Hospital Anxiety and Depression Scale in adult patients who are allogeneic HSCT candidates.
次要结局
- Satisfaction among patients and providers participating in the collaborative care model(Day 0)
- Severity of post-transplant outcomes as defined by an investigator-designed post-transplant outcome index in relation to Hospital Anxiety and Depression Scale scores(Day 0)
- Change in anxiety or depression as measured by the Hospital Anxiety and Depression Scale.(Day 0)