DiPAR: Diagnosing Parkinson*s Disease by neuromuscular function evaluation - DiPAR

niversitair Medisch Centrum Groningen0 个研究点目标入组 90 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

暂无简介。

•All subjects
•- right*handed
•- informed consent
•- ability to hold a pen for at least half an hour
•PD patients
•- diagnosis according to the UK Parkinson*s Disease Society Brain Bank clinical diagnostic criteria
•- symptoms scored as Hoehn & Yahr I*III
•- age: >50 years
•Essential tremor
•- diagnosis according to the criteria defined by the Tremor Investigation Group for more than 5 years
•Enhanced physiological tremor
•- diagnosis based on polymyography
•Psychogenic tremor
•- diagnosis based on polymyography
•Dystonia (writer*s cramp or torticollis spasmodica)
•- clinical diagnosis of dystonia
•- last botulinum toxin treatment at least 2 months prior to study investigation
•Post*stroke spasticity
•- clinical diagnosis of post*stroke spasticity (afflicting at least right hand function)

•All subjects
•- (other) neurological or motor disorder (than that included for)
•- Mini Mental State Examination (MMSE) score <26
•- Use of medication influencing movement other than for Parkinson's disease or essential tremor
•PD patients
•- Not willing to comply with overnight-withdrawal of Parkinson-related medication
•- Tremor-dominant PD
•ET patients
•- Not willing to comply with medication withdrawal, starting 7 days prior to study investigation

发起方