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临床试验/NCT06952985
NCT06952985已完成不适用

Role of Gum Chewing in Post-operative Gut Motility After Cesarean Section

Dr Maryam Aslam2 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2024年5月1日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
60
试验地点
2
主要终点
Mean Time of Passage of First flatus

研究概览

简要总结

Many women deliver by caesarean section nowadays. The proportion of women who deliver by caesarean section ranges from 15% to over 50%, in some countries. After a caesarean section it is common for the bowel to stop working for several hours or days. Although this usually resolves by itself in a few days, it may be very uncomfortable. The retained gases and stools can cause the mother's belly to become swollen and painful with cramps and she may feel nauseated and vomit so she is not able to eat. She may need additional medications to ease these symptoms and her hospital discharge may be delayed. The use of medications that relieve pain during labour and painkillers following the surgery can also delay bowel function. Small intestine activity after abdominal operations returns to normal function within a few hours, gastric activity returns to normal within 24-48 hours, and colon activity returns to normal within 48-72 hours. Due to the delayed motility of the gastrointestinal system in the postoperative period, gas and secretions accumulate in the stomach and small and large intestines, which causes abdominal distension, nausea, vomiting, and pain, all of which negatively affect the comfort level of the patients. Chewing sugar-free gum after cesarean section can promote the early recovery of gastrointestinal function, but the side effects of chewing gum are still unclear, which needs more clinical, large sample and high-quality studies to further verify.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Females of age 18-40 years
  • Parity <5
  • Presenting at gestational age ≥ 37 weeks,
  • Undergoing cesarean section (as per operational definition) under spinal anesthesia

排除标准

  • Females with history of chronic constipation (medical record)
  • Females with obstructed labour, hypothyroidism (TSH>5IU)
  • Females with intra operative complications such as bowel injury, history of gastrointestinal surgery, and water and electrolyte disturbances (on medical record), abnormal placenta (accrete, increta, previa, abruption)

结局指标

主要结局

Mean Time of Passage of First flatus

时间窗: 06 Months

In group A, females were given chewing gum 6 hours after the surgery, three times a day till passage of flatus. In group B, females were managed as per standard routine protocol i.e. allowing oral when bowel sounds are audible. Mean time of passage of first flatus since procedure was noted in terms of hours.

次要结局

  • Mean Duration of Hospital Stay(06 Months)

研究者

发起方
Dr Maryam Aslam
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Dr Maryam Aslam

Head of Department Gynaecology and Obstetrics

Combined Military Hospital Gujranwala

研究点 (2)

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