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临床试验/NCT06820697
NCT06820697尚未招募不适用

Expanding Access to HIV Self-test Kits: Sustaining Private Sector Channels That Enable Access to Preventive Health Services

University of California, San Francisco1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2027年1月15日最近更新:
干预措施

试验速览

阶段
不适用
状态
尚未招募
入组人数
200
试验地点
1
主要终点
Number of HIVST kits distributed to AGYW per shop month

研究概览

简要总结

New and innovative strategies are urgently needed to increase the uptake of HIV prevention and sexual and reproductive health services among adolescent girls and young women (AGYW) in sub-Saharan Africa. To ensure the real-world sustainability of free distribution of HIV self-test kits to AGYW by private drug shops and pharmacies, investigators will rigorously test supply-side subsidy structures for shopkeepers' provision of HIV-self test kits to AGYW combined with prosocial motivational supports. The combination of non-monetary and monetary support structures aims to emulate real-world health financing models for public-private partnerships and ultimately aims to improve equity in access to critical prevention services for AGYW at scale.

详细描述

This is an implementation-effectiveness trial that tests program adoption, implementation, and maintenance of free HIV self-test kit (HIVST) distribution to adolescent girls and young women (AGYW) financed by profits from HIVST kit sales to non-AGYW customers. To initiate adoption, the study will offer pharmacy and drug shopkeepers the opportunity to procure subsidized HIVST to simultaneously distribute to AGYW for free (reimbursed by the study mimicking government-supported provision) and sell to non-AGYW customers for profit, gradually phasing out procurement subsidies over 36 months to test maintenance of the segmented pricing model for real-world sustainability (Aim 1). Investigators will implement non-monetary motivation boosters to sustain shopkeeper engagement over the study period and use mixed-methods to understand shopkeepers' experiences and necessary conditions for program maintenance and provider behavior change (Aim 2), which will inform the co-design of a progressive scale-up plan to achieve national coverage with Tanzanian AGYW, public, and private partnership stakeholders (Aim 3). At the study's conclusion, investigators will have a comprehensive understanding of the support structures shops need to sustain HIVST kit provision for AGYW. Importantly, the study will contribute to generalizable learning about the structures required for commercially sustainable public-private partnerships for high-impact public health interventions.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Single Group
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Owners/staff of retail drug shops and pharmacies located in the study regions
  • Age 18 and older

排除标准

  • Refusal to install and track sales and distribution of HIVST kits using the Maisha Meds data system provided.

研究组 & 干预措施

High subsidy

Experimental

The high subsidy group will start off with a 90% subsidy for purchasing HIV self-test kits to sell in their shops.

干预措施: High HIVST kit subsidy (Behavioral)

Low subsidy

Active Comparator

The low subsidy group will start off with a 50% subsidy for purchasing HIV self-test kits to sell in their shops.

干预措施: Low HIVST kit subsidy (Behavioral)

结局指标

主要结局

Number of HIVST kits distributed to AGYW per shop month

时间窗: 39 months

HIVST kit distribution per shop per month will be tracked via Maisha Meds sales and inventory management system. The data from Maisha Meds will include a tag that identifies the kit recipient as an AGYW and will include the price paid for the HIVST kit ($0 for AGYW).

次要结局

  • Adoption(39 months)
  • Implementation 2(39 months)
  • Implementation 4(39 months)
  • Implementation 1(39 months)
  • Implementation 3(39 months)
  • Maintenance(39 months)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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