TCTR20190805004招募中未知
Association of Hypoxia Measured by Oxygen Desaturation Index (ODI) in OSA with Delis-Kaplan Executive Function System (D-KEFS) Tests in Middle-Aged and Older Adults
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 入组人数
- 29
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 50 Years 至 100 Years（—）
- 性别
- All
入选标准
- •1. Newly diagnosed with moderate to severe OSA by a split-night laboratory polysomnography (apnea hypopnea index ≥ 15)
排除标准
- •1.Severe systemic diseases : cirrhosis (Child-Pugh score B or C), chronic kidney disease stage 3 or more, pulmonary disease with chronic hypoxia or hypercarbia, heart failure NYHA II or more
- •2.Psychiatric illness
- •3.Neurological diseases : brain tumor, stroke, epilepsy, coma, history loss of consciousness of more than 30 mins after head trauma, encephalitis
- •4.Use of psychotropic medications
- •5.Alcohol or illicit drug abuse
- •6.Prior therapy for OSA
- •7.Sleep disorders other than OSA including central sleep apnea, insomnia, REM behavioral disorder, restless leg syndrome, periodic limb movement disorder, narcolepsy
- •8.Thai Mental State Examination score < 24
- •9.Inability to complete neuropsychological assessments or not fluent in Thai
- •10.Contraindications for MRI: presence of cardiac pacemaker or defibrillator, presence of metallic implants, claustrophobia, or uncomfortable or unable to lie down still for the MRI.
研究者
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