ISRCTN30703970已完成2 期
Oral thiamine (Vitamin B1) supplementation in subjects with type 2 diabetes mellitus: a randomised, double-blind, placebo-controlled crossover trial assessing biophysical markers of endothelial function, oxidant stress, insulin sensitivity and vascular inflammation
Portsmouth Hospitals NHS Trust (UK)0 个研究点目标入组 34 人开始时间: 2010年1月4日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 34
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Individuals with a diagnosis of type 2 diabetes mellitus with a more than 30% chance of cardiovascular disease (ischaemic heart disease, cerebrovascular disease or peripheral vascular disease) over the next 10 years
- •2. HbA1c less than 10%
- •3. Between the ages of 18 and 75 years, either sex
排除标准
- •1. Established cardiovascular disease (ischaemic heart disease, cerebrovascular disease or peripheral vascular disease)
- •2. Allergy/intolerance to thiamine supplementation
- •3. Insulin treatment
- •4. Diuretic treatment
- •5. Current multivitamin/thiamine therapy
- •6. Abnormal thyroid function
- •7. Chronic excess alcohol consumption/impaired liver function (greater than 21 units per week in females, greater than 28 units per week in males; Department of Health Guidelines)
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