The Effect of Systemic Dietary Instruction on Management of Plasma Phosphorus Levels in Peritoneal Dialysis (PD) Patients
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Plasma phosphorus levels
研究概览
简要总结
Hyperphosphatemia is highly prevalent in PD patients, and it is an independent risk factor for all-cause and cardiovascular mortality in these patients. Effective treatments are limited in suppressing plasma phosphorous. Because of the nearly linear relationship between protein and phosphorus intake, high dietary protein intake (DPI, 1.2-1.3g/kg/d recommended by KDOQI) would load high phosphorus burden in PD patients. It is suggested that hyperphosphatemia is hard to avoid under such a DPI level, even as the patients take sufficient phosphorus blinders and receive high PD dosage. The present study is to investigate whether systemic dietary instruction would show effects on control of hyperphosphatemia in PD patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Stable on PD for at least three month
- •Aged from 18 to 75 years old
- •Informed consent approval
排除标准
- •Malnutrition (based on SGA results)
- •Infection or inflammation within 1 month
- •Concurrent wasting disease (i.e. cancer, tuberculosis)
结局指标
主要结局
Plasma phosphorus levels
时间窗: up to 1 year
次要结局
- Plasma calcium levels(up to one year)
- Carotid artery intima-media thicknesses(up to 1 year)
- Plasma albumin levels(up to 1 year)