Optical CoherenCe tomography-gUided coronary intervention in Patients with complex lesIons: a randomized controlled trial (OCCUPI trial)

Yonsei University Health System, Severance Hospital0 个研究点目标入组 1,604 人开始时间: 待定最近更新: 2024年3月4日

试验速览

暂无简介。

•Age 19-85 years
•- Patients with ischemic heart diseases (including stable angina, unstable angina and acute myocardial infarction) presented with typical chest pain or objective evidences of myocardial ischemia (positive invasive or non-invasive studies,
•electrocardiogram (ECG) consistent with ischemia, or elevated cardiac enzymes)
•- Complex coronary stenotic lesions (>50% based on visual estimate) considered for coronary revascularization with DES
•- Definition of complex lesions (at least one):
•? Acute myocardial infarction
•? Chronic total occlusion
•? Long lesion: expected stent length =28mm based on angiographic estimation
•? Calcified lesion
•? Bifurcation (including all techniques, one- or two-stent)
•? Unprotected left main disease
•? Small vessel diseases with reference vessel diameter less than 2.5 mm
•? Intracoronary thrombus visible on the angiography
•? Stent thrombosis
•? In-stent restenosis
•- Patients who provide signed informed consent

•- Severe hepatic dysfunction (=3 times normal reference values)
•- Significant renal dysfunction (Serum creatinine >2.0 mg/dL)
•- Platelet count <100,000 cells/mm3 or >700,000 cells/mm3, a white blood cell count of <3,000 cells/mm3, hemoglobin <8.0 g/dL, or other known bleeding diathesis
•- Hemodynamically unstable during procedures or cardiogenic shock
•- Pregnant women or women who might be pregnant
•- Life expectancy; less than 1 year
•- Inability to understand or read the informed content

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