Visual Performance After Optically Correcting the Eye's Aberration With a Spatial Light Modulator
试验速览
- 阶段
- 不适用
- 入组人数
- 30
- 主要终点
- Visual acuity
研究概览
简要总结
Eye's aberrations have been known to degrade human visual performance and the visual performance is significantly improved when correcting the aberrations in the central visual field. However, how the aberration correction affects the peripheral visual performance is not well understood. Moreover, how central and peripheral vision interacts remains unclear.
To conduct the study, we will use an adaptive optics vision simulator equipped with a Shack-Hartmann wavefront sensor and a spatial light modulator (see details in procedures section of the protocol). This system is capable of noninvasively controlling the eye's optical quality and evaluating visual performance simultaneously over a wide area of visual space. This study provides insights into the visual performance in the periphery visual field, and interaction between central and peripheral visual fields.
The goal of this study is to evaluate the visual performance at central and peripheral visual fields after correcting the ocular aberrations. An optical system equipped with a liquid crystal spatial light modulator will be used to achieve this goal non-invasively.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •A person is eligible for inclusion in the study if he/she:
- •Is between the ages of 18 and
- •Has normal corneas i.e. no corneal infections, no systemic pink eye, no clinically significant dry eye, and no corneal dystrophies.
- •Has refractive errors less than +/- 10.0 Diopters in both eyes.
排除标准
- •A person will be excluded from the study if he/she:
- •Adults between the ages of 18-60 who are unable to give informed consent
- •Individuals below 18 years old
- •Individuals above the age of 60
- •Pregnant women (self-reporting, hormonal changes may alter the refractive status of the eye)
- •Prisoners
- •Students for whom you have direct access to/influence on grades
- •People who do not understand or speak English
- •Has clinically significant dry eye.
- •Has clinically significant cataract.
- •Has spherical refractive error that exceeds the limits outlined above.
- •Is unable to hold his or her head steady for the duration of study measurements.
研究组 & 干预措施
normal healthy group
Spatial light modulator
干预措施: Spatial light modulator (Device)
结局指标
主要结局
Visual acuity
时间窗: up to 6 separate sessions (each session taking up to 2 hours)
Snellen "Tumbling E" method will be used to determine the smallest letter that a subject can see.
Contrast sensitivity
时间窗: up to 6 separate sessions (each session taking up to 2 hours)
Light and dark sinusoidal stripes (Gabor gratings) will used to determine the smallest contrast that a subject can see
Contrast perception
时间窗: up to 6 separate sessions (each session taking up to 2 hours)
Light and dark sinusoidal stripes (Gabor gratings) will used to determine differences in contrast perceived by the central and peripheral visual system
次要结局
未报告次要终点
研究者
Geunyoung Yoon
Professor
University of Houston