NCT02047695已完成不适用
Women With Migraine With Aura Neuroimaging (WOMAN) Study: A Population-based Study of Danish Twins
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 345
- 主要终点
- Evidence of white matter hyperintensities or subclinical ischaemic stroke confirmed by MRI
研究概览
简要总结
The purpose of this study is to investigate whether a particular form of migraine, migraine with aura, is associated with structural changes in the brain
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 30 Years 至 60 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •case (migraine with aura), co-twin to case, or control (migraine-free)
- •residency in Denmark
- •no severe neurological (vascular, neurodegenerative or neuroinflammatory) disorders, or other somatic or psychiatric disorders
排除标准
- •residency outside Denmark
- •registered in Civil Registry as not to be contacted by researchers
- •severe neurological (vascular, neurodegenerative or neuroinflammatory) disorders, or other somatic or psychiatric disorders
- •mobile metal parts or other contraindication for MRI
- •weight of 130+ kilograms
- •pregnancy
- •subjects that wished not to be informed about abnormal findings on MRI
- •chronic tension-type headache, medication overuse headache, or cluster headache (diagnosed through physician interview)
- •frequent tension-type headache (control group only, self-reported or diagnosed through physician interview)
结局指标
主要结局
Evidence of white matter hyperintensities or subclinical ischaemic stroke confirmed by MRI
时间窗: At time of MRI
次要结局
- Evidence of other structural and functional changes in brain(At time of MRI)
研究者
David Gaist
professor, consultant
Odense University Hospital
相似试验
Unknown
不适用
Longitudinal Changes of Brain Functional Connectivity in MigraineMigraineNCT03487978Samsung Medical Center100
已完成
不适用
fMRI of the Brainstem in Migraine Sufferers and Controls. Does Iron Deposition Correlate With Progression of Disease?Episodic MigraineChronic Daily MigraineNCT00868556The Cleveland Clinic33
进行中（未招募）
不适用
Observational Study of Oral Atogepant to Evaluate Real-World Effectiveness in Adult Participants With MigraineMigraineNCT06543914AbbVie1,314
招募中
不适用
Migraine With Aura and Patent Foramen Ovale: Identification of Biomarkers to Select Patients In Whom Intervention Would Be Beneficial (MANET)Migraine HeadachePFO - Patent Foramen OvaleNCT06046508Centro Cardiologico Monzino120
已完成
不适用
Migraine With and Without Aura Characteristics and Response to Remote Electrical Neuromodulation (REN) TreatmentMigraine With AuraMigraine Without AuraNCT06023953Theranica31,715