Quality of Life in Barrett's Esophagus and GERD:GERD Symptoms, Perception of Cancer Risk, and Actual Cancer Risk
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 89
- 试验地点
- 1
- 主要终点
- Health State Utility as measured by the Time Trade-off (TTO) method/Standard Gamble (SG) method
研究概览
简要总结
To Compare the overall quality of life of patients with no Barrett's esophagus , non-dysplastic Barrett's Esophagus (NDBE), Barrett's esophagus with low grade dysplasia (LGD), and Barrett's esophagus with high grade dysplasia (HGD). We also Compare the overall quality of life of Barrett's esophagus patients with severe gastroesophageal reflux disease (GERD) symptoms to those with no GERD symptoms
详细描述
The presence of GERD symptoms is associated with a significant decrease in quality of life.While a diagnosis of Barrett's esophagus is also associated with a decrease in quality of life, these studies evaluated Barrett's esophagus patients with GERD symptoms.It is unclear whether decrements in quality of life from cancer risk in patients with Barrett's esophagus are due to actual cancer risk or a patient's false perception.Here we Compare the overall quality of life of patients with no Barrett's esophagus , non-dysplastic Barrett's Esophagus (NDBE), Barrett's esophagus with low grade dysplasia (LGD), and Barrett's esophagus with high grade dysplasia (HGD). The Investigators will also Compare the overall quality of life of Barrett's esophagus patients with severe gastroesophageal reflux disease (GERD) symptoms to those with no GERD symptoms. Finally the investigators will compare the overall quality of life of patients with a perceived low risk of esophageal cancer to those with a perceived high risk of esophageal cancer
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18 or above
- •At least one of the following:
- •Previous diagnosis of Barrett's esophagus Presence of GERD symptoms per patient report
排除标准
- 未提供
结局指标
主要结局
Health State Utility as measured by the Time Trade-off (TTO) method/Standard Gamble (SG) method
时间窗: 1 year
questionnaire
次要结局
- SF-36 physical function (PF) subscale(12 months)
- SF-36 role limitations-physical (RP) subscale(12 months)
- SF-36 general health (GH) subscale(12 months)
研究者
PRATEEK SHARMA
Principal Investigator
Midwest Biomedical Research Foundation