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临床试验/NCT00558350
NCT00558350已完成不适用

Systemic, Intrapulmonary and Pleural Inflammatory Reaction in Patients Undergoing Thoracic Surgery

University Hospital, Basel, Switzerland1 个研究点 分布在 1 个国家目标入组 15 人开始时间: 2007年4月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
15
试验地点
1
主要终点
Cytokine levels in blood, bronchial lavage fluid and pleural fluid

研究概览

简要总结

Inflammatory reaction in different compartments of the body may have a negative effect on outcome. This study assesses the inflammatory reaction systemically, intrapulmonary and intrapleural by measuring different cytokines. Patients with lung cancer undergoing lobectomy or segmentectomy are included in the study. Hypothesis: The inflammatory reaction in the pleural space is high compared to the systemic and intrapulmonary ones.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
20 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • elective lobectomy
  • elective segmentectomy
  • 20-90 years
  • informed consent given

排除标准

  • emergency operations
  • pneumonectomy

结局指标

主要结局

Cytokine levels in blood, bronchial lavage fluid and pleural fluid

时间窗: 2 years

Correlation between cytokine levels and pulmonary morbidity

时间窗: 2 years

次要结局

  • Comparison of this collective with transthoracic esophagectomies and evaluation of the inflammatory reactions (esophageal collective registered:NCT00512265)(4 years)

研究者

发起方
University Hospital, Basel, Switzerland
申办方类型
Other
责任方
Sponsor

研究点 (1)

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