Spatial Cognitive Training for Chronic Vestibular Disorders
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 主要终点
- Change from baseline in Dizziness Handicap Inventory
研究概览
简要总结
In this study the investigators propose to apply cognitive training, which has been largely used in the realm of age-related cognitive decline, dementia, and Alzheimer's disease, in a novel clinical context to individuals with vestibular impairment. In prior work the investigators observed that individuals with vestibular loss have evidence of spatial cognitive impairment. The investigators plan to evaluate the preliminary efficacy and feasibility of a cognitive training program in a sample of participants with chronic vestibular impairment who display deficits in spatial ability. The cognitive training program will focus on visuospatial skills and will be used as an adjunct to traditional vestibular physical therapy (VPT).
详细描述
Patients with chronic vestibular dysfunction with report symptoms of spatial cognitive impairment will be offered cognitive training. The intervention will consist of a well-validated cognitive training protocol that specifically targets spatial navigation skills. The protocol was developed by Willis et al. for the Adult Development and Enrichment Trial (ADEPT) trial, which trains map reading and route-learning skills through mental rotation training tasks over the course of 5 weeks. Patients will be assessed by study staff pre-intervention, immediately post-intervention and at 3 months post-intervention using spatial cognitive outcomes, quality of life measures, and gait and balance outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of chronic vestibular disorder (>6months & diagnosis from laboratory testing by neuro-otologist)
排除标准
- •Participants with dementia, or with blindness or deafness who cannot participate in cognitive training procedures.
研究组 & 干预措施
Spatial Cognitive Training
map reading and route-learning skills
干预措施: Spatial Cognitive Training (Behavioral)
结局指标
主要结局
Change from baseline in Dizziness Handicap Inventory
时间窗: Baseline vs immediately post-training
Subjective 25-item questionnaire measuring Quality of Life and disability on a scale from 0-100
Change from immediate post-training to 3-months post-training in Dizziness Handicap Inventory
时间窗: Immediately post-training to 3 months post-training
Subjective 25-item questionnaire measuring Quality of Life and disability on a scale from 0-100
Change from baseline in Four Square Step Test
时间窗: Baseline vs immediately post-training
Assesses dynamic balance, spatial, \& sequencing skills while stepping forward/back/sideways over a low obstacle (measured in seconds)
Change from immediate post-training to 3-months post-training in Four Square Step Test
时间窗: Immediately post-training to 3 months post-training
Assesses dynamic balance, spatial, \& sequencing skills while stepping forward/back/sideways over a low obstacle (measured in seconds)
Change from baseline in Dynamic Gait Index
时间窗: Baseline vs immediately post-training
Balance challenges during 8 different gait tasks (head turns, speed changes, over/around obstacles) with total score out of 24 points.
Change from immediate post-training to 3-months post-training in Dynamic Gait Index
时间窗: Immediately post-training to 3 months post-training
Balance challenges during 8 different gait tasks (head turns, speed changes, over/around obstacles) with total score out of 24 points.
次要结局
- Change from baseline in Money Road Map Test(Baseline vs immediately post-training)
- Change from baseline in Santa Barbara Sense of Direction Scale(Baseline vs immediately post-training)
- Change from immediate post-training to 3-months post-training in Santa Barbara Sense of Direction Scale(Immediately post-training to 3 months post-training)
- Change from immediate post-training to 3-months post-training in Money Road Map Test(Immediately post-training to 3 months post-training)
- Change from baseline in Benton Visual Retention Test(Baseline vs immediately post-training)
- Change from baseline in modified Clinical Test of Sensory Organization and Balance(Baseline vs immediately post-training)
- Change from baseline in Activities-specific Balance Confidence Scale(Baseline vs immediately post-training)
- Change from immediate post-training to 3-months post-training in Activities-specific Balance Confidence Scale(Immediately post-training to 3 months post-training)
- Change from immediate post-training to 3-months post-training in modified Clinical Test of Sensory Organization and Balance(Immediately post-training to 3 months post-training)
- Change from immediate post-training to 3-months post-training in Benton Visual Retention Test(Immediately post-training to 3 months post-training)
研究者
Brooke Klatt
Postdoctoral Research Fellow
University of Pittsburgh