Training-induced Cerebral Reorganization in Schizophrenia

Not Applicable

Completed

• Conditions: Schizophrenia

• Registration Number: NCT00695708
• Lead Sponsor: University of Konstanz

Brief Summary

The purpose of this study is to reveal the effects of computer-aided cognitive-auditory training on cerebral reorganization in schizophrenia.

Detailed Description

Impairment in cognitive functions is one of the main symptoms in schizophrenia and is currently one of the challenges in the treatment of the disease.

In this study we compare effects of two computer-aided training programs. One focused on auditory perception and processing as a basic ability underlying higher order information processing.

The other training involves a variability of cognitive abilities.

Both trainings are computer-aided and time-intensive, including up to twenty sessions within four weeks.

Study Timeline

• Study Start: 2008-01
• Status Verified: 2008-06
• Study First Submitted: 2008-06-09
• Study First Submitted QC: 2008-06-09
• Study First Posted: 2008-06-12
• Primary Completion: 2009-06
• Study Completion: 2010-01
• Last Update Submitted: 2010-04-12
• Last Update Posted: 2010-04-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Clinical diagnosis of schizophrenia and disorders with psychotic features
• Intact hearing abilities

Exclusion Criteria

• Mental retardation
• Age over 60
• Insufficient German language knowledge

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Event related potential MEG, test scores in word fluency and verbal learning tasks	pre and post intervention

Secondary Outcome Measures

Name	Time	Method
Symptom severity, GAF score	pre and post intervention

Trial Locations

Locations (1)

University of Konstanz; 🇩🇪 Konstanz, Baden Württenberg, Germany