Training-induced Cerebral Reorganization in Schizophrenia
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Schizophrenia
- Sponsor
- University of Konstanz
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Event related potential MEG, test scores in word fluency and verbal learning tasks
- Status
- Completed
- Last Updated
- 16 years ago
Overview
Brief Summary
The purpose of this study is to reveal the effects of computer-aided cognitive-auditory training on cerebral reorganization in schizophrenia.
Detailed Description
Impairment in cognitive functions is one of the main symptoms in schizophrenia and is currently one of the challenges in the treatment of the disease. In this study we compare effects of two computer-aided training programs. One focused on auditory perception and processing as a basic ability underlying higher order information processing. The other training involves a variability of cognitive abilities. Both trainings are computer-aided and time-intensive, including up to twenty sessions within four weeks.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Clinical diagnosis of schizophrenia and disorders with psychotic features
- •Intact hearing abilities
Exclusion Criteria
- •Mental retardation
- •Age over 60
- •Insufficient German language knowledge
Outcomes
Primary Outcomes
Event related potential MEG, test scores in word fluency and verbal learning tasks
Time Frame: pre and post intervention
Secondary Outcomes
- Symptom severity, GAF score(pre and post intervention)