Cognitive Training and Practice Effects in Mild Cognitive Impairment
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Mild Cognitive Impairment
- Sponsor
- University of Utah
- Enrollment
- 197
- Locations
- 1
- Primary Endpoint
- Auditory Memory Attention Index
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
The current study will test the effectiveness of a computerized cognitive training program on auditory memory and attention in patients with mild cognitive impairment. Practice effects will also be examined as a moderator of treatment response.
Detailed Description
The current study will test the effectiveness of a computerized cognitive (thinking) training program on improving thinking and memory in patients with mild cognitive impairment. The investigators will also examine how short term changes in thinking abilities (i.e., practice effects) can be related to improvement in thinking abilities after the cognitive training program.
Investigators
Kevin Duff
Associate Professor of Neurology
University of Utah
Eligibility Criteria
Inclusion Criteria
- •Mild Cognitive Impairment, amnestic subtype
- •65 years of age or older
- •Availability of a knowledgeable informant
- •Access to internet 3 hours per week
- •Adequate vision, hearing, and motor responding to participate in training
Exclusion Criteria
- •History of major stroke, head injury with loss of consciousness of \>30 minutes, or other neurological disorder or systemic illness that are thought to be affecting cognition (e.g., seizure disorder, demyelinating disorder, etc.)
- •Current or past major psychiatric illness (e.g., schizophrenia, bipolar affective disorder)
- •History of substance abuse
- •Current use of antipsychotics or anticonvulsant medications
- •Currently residing in a nursing home or other skilled nursing facility
Outcomes
Primary Outcomes
Auditory Memory Attention Index
Time Frame: 13 weeks
This is a composite of six subtests of the Repeatable Battery for the Assessment of Neuropsychological Status. It is a standard score (mean=100, standard deviation=15), with a range of approximately 45 - 145, with higher scores indicating better outcome.