Computer-Based Training for Mild Alzheimer's Disease
Phase 1
Completed
- Conditions
- Alzheimer's Disease
- Registration Number
- NCT00319891
- Lead Sponsor
- Posit Science Corporation
- Brief Summary
The primary objective of this study is to evaluate the effects of computer-based training program ("HiFi-AD") on the memory and cognitive abilities of individuals diagnosed with mild Alzheimer's Disease (AD).
- Detailed Description
The purpose of this study is to determine the extent to which computer-based cognitive remediation improves cognitive functions using standardized neuropsychological assessments relevant to AD; 2) the acceptability and feasibility of using computer-based cognitive remediation in an AD population.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 6
Inclusion Criteria
- Fluent in English.
- Mini-Mental Status Examination (MMSE) score of 22 or higher.
- Adequate visual capacity.
- Adequate hearing capacity.
- Has a caregiver with some computer experience.
- Willing and able to commit to the time requirement of the entire study.
Exclusion Criteria
- Clinically significant cerebrovascular disease.
- Participant is planning to begin acetylcholinesterase inhibitor (AChEI) therapy.
- Participants with severe tremor.
- Axis 1 or 2 psychiatric disorders.
- History of substance abuse.
- History of head trauma.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method The primary objective of this trial will be to assess the feasibility of using computer-based cognitive training in an a population with early Alzheimer's Disease.
- Secondary Outcome Measures
Name Time Method A standardized set of neuropsychological assessments will be conducted pre- and post- compuer-based training.
Trial Locations
- Locations (1)
University of California, San Francisco
🇺🇸San Francisco, California, United States
University of California, San Francisco🇺🇸San Francisco, California, United States