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Clinical Trials/NCT00319891
NCT00319891
Completed
Phase 1

Computer-Based Training for Mild Cognitive Impairment and Mild Alzheimer's Disease

Posit Science Corporation1 site in 1 country6 target enrollmentSeptember 2004

Overview

Phase
Phase 1
Intervention
Not specified
Conditions
Alzheimer's Disease
Sponsor
Posit Science Corporation
Enrollment
6
Locations
1
Primary Endpoint
The primary objective of this trial will be to assess the feasibility of using computer-based
Status
Completed
Last Updated
12 years ago

Overview

Brief Summary

The primary objective of this study is to evaluate the effects of computer-based training program ("HiFi-AD") on the memory and cognitive abilities of individuals diagnosed with mild Alzheimer's Disease (AD).

Detailed Description

The purpose of this study is to determine the extent to which computer-based cognitive remediation improves cognitive functions using standardized neuropsychological assessments relevant to AD; 2) the acceptability and feasibility of using computer-based cognitive remediation in an AD population.

Registry
clinicaltrials.gov
Start Date
September 2004
End Date
October 2006
Last Updated
12 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Fluent in English.
  • Mini-Mental Status Examination (MMSE) score of 22 or higher.
  • Adequate visual capacity.
  • Adequate hearing capacity.
  • Has a caregiver with some computer experience.
  • Willing and able to commit to the time requirement of the entire study.

Exclusion Criteria

  • Clinically significant cerebrovascular disease.
  • Participant is planning to begin acetylcholinesterase inhibitor (AChEI) therapy.
  • Participants with severe tremor.
  • Axis 1 or 2 psychiatric disorders.
  • History of substance abuse.
  • History of head trauma.

Outcomes

Primary Outcomes

The primary objective of this trial will be to assess the feasibility of using computer-based

cognitive training in an a population with early Alzheimer's Disease.

Secondary Outcomes

  • A standardized set of neuropsychological assessments will be conducted pre- and post-
  • compuer-based training.

Study Sites (1)

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