The Effect of Computerized Cognitive Training on Mood and Thinking Style Amongst Patients in Inpatient Settings

Not Applicable

Completed

• Conditions: Anxiety; Anhedonia; Depression
• Interventions: Behavioral: Cognitive Control Training (CCT); Behavioral: Positive Mental Imagery Training (PMIT); Other: Treatment as Usual

• Registration Number: NCT02958228
• Lead Sponsor: Ruhr University of Bochum

Brief Summary

The purpose of this randomized controlled trial is to establish feasibility and provide initial estimates of efficacy of two computerized cognitive training procedures (a form of Positive Mental Imagery Training, PMIT, and a form of Cognitive Control Training, CCT) delivered as adjuncts to treatment as usual (TAU) in inpatient mental health treatment settings.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-11
• Study First Submitted: 2016-11-04
• Study First Submitted QC: 2016-11-07
• Study First Posted: 2016-11-08
• Primary Completion: 2017-12
• Status Verified: 2018-03
• Study Completion: 2018-03
• Last Update Submitted: 2018-03-27
• Last Update Posted: 2018-03-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 57

Inclusion Criteria

• Aged 18 years or above
• Sufficient German language skills
• Receiving treatment in a participating inpatient clinic during the timeframe of the study (i.e. they must be able to complete the training entirely within their admission).

Exclusion Criteria

• Existence of a condition or circumstances that would interfere with completion of the study procedures (e.g. severe visual impairment, neurological problem, acute psychosis or substance withdrawal symptoms)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Cognitive Control Training (CCT)	Cognitive Control Training (CCT)	An adaptive Paced Auditory Serial Addition Task (PASAT), adapted from that applied in previous studies (e.g. Siegle et al., 2007; Hoorelbeke et al., 2015). The intervention consists of 8 sessions completed over a period of 2 weeks. The training takes place alongside participants' treatment as usual (TAU) in the inpatient setting.
Cognitive Control Training (CCT)	Treatment as Usual	An adaptive Paced Auditory Serial Addition Task (PASAT), adapted from that applied in previous studies (e.g. Siegle et al., 2007; Hoorelbeke et al., 2015). The intervention consists of 8 sessions completed over a period of 2 weeks. The training takes place alongside participants' treatment as usual (TAU) in the inpatient setting.
Positive Mental Imagery Training (PMIT)	Positive Mental Imagery Training (PMIT)	Computerized Positive Mental Imagery Training (PMIT), a form of mental imagery-based cognitive bias modification adapted from previous experimental (e.g. Holmes, Lang, \& Shah, 2009) and clinical (e.g. Blackwell \& Holmes, 2010) work. The intervention consists of 8 sessions completed over a period of 2 weeks. The training takes place alongside participants' treatment as usual (TAU) in the inpatient setting.
Positive Mental Imagery Training (PMIT)	Treatment as Usual	Computerized Positive Mental Imagery Training (PMIT), a form of mental imagery-based cognitive bias modification adapted from previous experimental (e.g. Holmes, Lang, \& Shah, 2009) and clinical (e.g. Blackwell \& Holmes, 2010) work. The intervention consists of 8 sessions completed over a period of 2 weeks. The training takes place alongside participants' treatment as usual (TAU) in the inpatient setting.
Treatment as Usual	Treatment as Usual	Participants will receive their treatment as usual (TAU) within the inpatient setting, which may include group/individual psychological therapy, a range of therapeutic activities, and pharmacological treatment.

Primary Outcome Measures

Name	Time	Method
21-item positive subscale from the extended Positive and Negative Affect Schedules	Post-intervention (2 weeks post-baseline)	The Joviality, Self-Assurance, Attentiveness, and Serenity subscales of the extended PANAS (PANAS-X; Watson \& Clark, 1994) will be administered, following previous experimental research examining the effect of positive mental imagery on state mood (e.g. Holmes, Lang, \& Shah, 2009). Participants will be asked to rate the items according to how they have been feeling 'in the past week, that is, during the past seven days, including today'.

Secondary Outcome Measures

Name	Time	Method
21-item positive subscale from the extended Positive and Negative Affect Schedules	Baseline, Follow-up (2 weeks after the post-intervention assessment)	The Joviality, Self-Assurance, Attentiveness, and Serenity subscales of the extended PANAS (PANAS-X; Watson \& Clark, 1994) will be administered, following previous experimental research examining the effect of positive mental imagery on state mood (e.g. Holmes, Lang, \& Shah, 2009). Participants will be asked to rate the items according to how they have been feeling 'in the past week, that is, during the past seven days, including today'.
Dimensional Anhedonia Rating Scale	Baseline, Post-intervention (2 weeks post-baseline), Follow-up (2 weeks after the post-intervention assessment)	An extended 26-item version of the Dimensional Anhedonia Rating Scale (DARS; Rizvi et al., 2015) will be administered.
Quick Inventory of Depressive Symptomatology - Self Report	Baseline, Post-intervention (2 weeks post-baseline), Follow-up (2 weeks after the post-intervention assessment)
GAD-7	Baseline, Post-intervention (2 weeks post-baseline), Follow-up (2 weeks after the post-intervention assessment)
Positive Mental Health Scale	Baseline, Post-intervention (2 weeks post-baseline), Follow-up (2 weeks after the post-intervention assessment)
Prospective Imagery Test	Baseline, Post-intervention (2 weeks post-baseline)
Scrambled Sentences Test (SST)	Baseline, Post-intervention (2 weeks post-baseline)
Implicit Associations Test (IAT)	Baseline, Post-intervention (2 weeks post-baseline)

Trial Locations

Locations (2)

Nexus-Klinik; 🇩🇪 Baden-Baden, Germany

St. Marien Hospital Eickel; 🇩🇪 Herne, Germany