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临床试验/NCT07766447
NCT07766447尚未招募不适用

Long-term Medical Impact of War Injuries on Military Personnel

Direction Centrale du Service de Santé des Armées0 个研究点目标入组 20 人开始时间: 2026年10月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
20
主要终点
The primary outcome is the feasibility of a standardized multidisciplinary follow-up strategy, assessed by patient recruitment rate, retention rate during follow-up, completion

研究概览

简要总结

Beyond short-term multidisciplinary care, the French Armed Forces Health Service provides medical and surgical care, followed by medical and social care and long-term support for the wounded, especially when they have suffered multiple injuries during operations and are severely disabled. This involves primary phases of rehabilitation to limit the after-effects, preserve the functional prognosis and increase the autonomy of the injured person; secondary medical and social phases of rehabilitation and reintegration to restore the injured person's place in society.

The reconstruction stages are therefore essential. However, little data is available on the evolution of these patients' general health.

A similar follow-up cohort was set up by the British Army to monitor physical injuries during the conflict in Afghanistan. The results suggest the possibility of long-term cardiovascular and neoplastic complications in this population.

Furthermore, there is no data available on the evolution of the health status of war wounded in France. A retrospective study is currently underway, TRAUM-IMPACT RETRO, with the aim of assessing the consequences of 10 years of operational engagements from 2013 to 2023. This study should enable the medical French army service to clarify the topography of injuries and the medical and social outcomes of casualties treated at the Percy National Military Institute of Surgery (HNIA Percy) during this period. Initially, a pilot study followed by a cohort study will enable the investigators to standardise the medical follow-up of war casualties and determine their medical and social outcomes.

The population studied in this clinical trial corresponds to all military personnel repatriated and treated at the Percy National Military Hospital for a war injury defined as follows: "Any physical injury of a certain degree of severity directly related to the presence of the enemy, i.e. in combat or indirectly through effective participation in war operations, preparatory to or consequential to combat. " The investigators hypothesise that severely disabled wounded soldiers are at risk of specific complications leading to excess morbidity and disability, complications associated with ageing, and a risk of social and professional isolation. As a result, the participants require lifelong monitoring to prevent, detect and manage these complications, thereby ensuring that the nation gives its wounded children the recognition the participants deserve.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Age ≥ 18 years
  • •French military patient
  • •Patient wounded in action
  • •Patient repatriated and treated at the Percy National Military Hospital for a physical war injury sustained between 2020 and 2025
  • •Life expectancy > 1 year
  • •Patient conscious and oriented at the time of inclusion
  • •Patient with health insurance

排除标准

  • •Isolated psychological injury
  • •Physical injury not related to war
  • •Patient unable to give free consent, under guardianship or curatorship
  • •Refusal to participate

研究组 & 干预措施

War wounded repatriated and treated at the Percy National Institute of Military Medicine

Experimental

干预措施: biological and radiological examinations (Other)

结局指标

主要结局

The primary outcome is the feasibility of a standardized multidisciplinary follow-up strategy, assessed by patient recruitment rate, retention rate during follow-up, completion

时间窗: 2 years

Health event reported during visits over the course of the study and type of injury at inclusion (multiple trauma, limb trauma, head trauma).

次要结局

  • Longitudinal evolution of quality of life according to type of injury(2 years)
  • Longitudinal changes in gait performance(2 yaers)
  • Define predictive factors for the occurrence of a new diagnosis or new treatment (psychiatric illness, chronic illness, cardiovascular disease, neoplasia, or any relevant medical event).(2 yaers)
  • Level of generic pain(2 years)
  • Level of anxiety and depression(2 years)
  • Sleep quality(2 years)
  • Level of physical inactivity(2 years)
  • Addictive behaviours(2 years)
  • Incidence of Post-Traumatic Stress Disorder(2 years)

研究者

发起方
Direction Centrale du Service de Santé des Armées
申办方类型
Other
责任方
Sponsor

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