Comparison of analgesic efficacy ofepidural analgesia with continuous transversusabdominis plane block in renal transplant recipients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- PGIMER
- 入组人数
- 62
- 试验地点
- 1
- 主要终点
- Numerical Pain rating scale score postoperatively
研究概览
简要总结
Although continuous TAPblock has been compared with epidural analgesia in laparoscopic surgeries, tothe best of our knowledge a study directly comparing the technique withepidural analgesia has not been performed in renal transplantrecipients. The existing study was designed to directly comparecontinuous TAP block with continuous patient controlled epidural blockade todetermine whether TAP block can provide a useful alternative to epiduralanalgesia in this subset of patients.
The studyhypothesizes that transversus abdominis plane block is a non inferior analgesictechnique to continuous epidural analgesia in renal transplant recipients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with end stage renal disease scheduled to undergo live donor renal transplant.
排除标准
- •1.Refusal to give consent.
- •2.Derangements of coagulation profile contraindicating the use of epidural anaesthesia (INR of ≥1.3 will be considered a cut-off for the study).
- •3.Addiction to opioids, or alcohol, or history of any other substance abuse.
- •4.Allergy to local anaesthetic drugs.
- •5.Extension of surgical incision lateral to anterior axillary line or above T8 dermatome.
- •6.Inability to communicate (e.g. known psychiatric disorders).
- •7.Accidental complications such as dural puncture or peritoneal breach.
结局指标
主要结局
Numerical Pain rating scale score postoperatively
时间窗: Numerical Pain rating scale score at 0, 1, 2, 4, 6, 12, 24 hours postoperatively
次要结局
- Requirement of postoperative opioid (fentanyl) in the first 24 hours postoperatively(24 hours postoperatively)
- Patient satisfaction with the analgesia regimen.(24 hours postoperatively)